[HTML][HTML] Modelling the course of an HIV infection: insights from ecology and evolution
The Human Immunodeficiency Virus (HIV) is one of the most threatening viral agents. This
virus infects approximately 33 million people, many of whom are unaware of their status …
virus infects approximately 33 million people, many of whom are unaware of their status …
[HTML][HTML] Stochastic theory of early viral infection: continuous versus burst production of virions
JE Pearson, P Krapivsky… - PLoS computational …, 2011 - journals.plos.org
Viral production from infected cells can occur continuously or in a burst that generally kills
the cell. For HIV infection, both modes of production have been suggested. Standard viral …
the cell. For HIV infection, both modes of production have been suggested. Standard viral …
Stochastic analysis of pre-and postexposure prophylaxis against HIV infection
The events that occur following HIV exposure, preceding any detectable infection, are
difficult to study experimentally. However, there is considerable evidence that these events …
difficult to study experimentally. However, there is considerable evidence that these events …
[HTML][HTML] Predicting HIV-1 transmission and antibody neutralization efficacy in vivo from stoichiometric parameters
OF Brandenberg, C Magnus, P Rusert… - PLoS …, 2017 - journals.plos.org
The potential of broadly neutralizing antibodies targeting the HIV-1 envelope trimer to
prevent HIV-1 transmission has opened new avenues for therapies and vaccines. However …
prevent HIV-1 transmission has opened new avenues for therapies and vaccines. However …
[HTML][HTML] Accurate predictions of population-level changes in sequence and structural properties of HIV-1 Env using a volatility-controlled diffusion model
O DeLeon, H Hodis, Y O'Malley, J Johnson… - PLoS …, 2017 - journals.plos.org
The envelope glycoproteins (Envs) of HIV-1 continuously evolve in the host by random
mutations and recombination events. The resulting diversity of Env variants circulating in the …
mutations and recombination events. The resulting diversity of Env variants circulating in the …
[HTML][HTML] Effect of stochasticity on coinfection dynamics of respiratory viruses
Background Respiratory viral infections are a leading cause of mortality worldwide. As many
as 40% of patients hospitalized with influenza-like illness are reported to be infected with …
as 40% of patients hospitalized with influenza-like illness are reported to be infected with …
[HTML][HTML] On the extinction probability in models of within-host infection: the role of latency and immunity
Not every exposure to virus establishes infection in the host; instead, the small amount of
initial virus could become extinct due to stochastic events. Different diseases and routes of …
initial virus could become extinct due to stochastic events. Different diseases and routes of …
Key positions of HIV-1 ENV and signatures of vaccine efficacy show gradual reduction of population founder effects at the clade and regional levels
ABSTRACT HIV-1 group M was transmitted to humans nearly one century ago. The virus
has since evolved to form distinct clades, which spread to different regions of the world. The …
has since evolved to form distinct clades, which spread to different regions of the world. The …
The probability of HIV infection in a new host and its reduction with microbicides
We use a simple mathematical model to estimate the probability and its time dependence
that one or more HIV virions successfully infect target cells. For the transfer of a given …
that one or more HIV virions successfully infect target cells. For the transfer of a given …
Periodic solution of a stochastic HBV infection model with logistic hepatocyte growth
F Xie, M Shan, X Lian, W Wang - Applied Mathematics and Computation, 2017 - Elsevier
In this paper, we present a stochastic hepatitis B virus (HBV) infection model with logistic
hepatocyte growth. We show that the stochastic differential equation (SDE) HBV model has …
hepatocyte growth. We show that the stochastic differential equation (SDE) HBV model has …