[HTML][HTML] Modelling the course of an HIV infection: insights from ecology and evolution

S Alizon, C Magnus - Viruses, 2012 - mdpi.com
The Human Immunodeficiency Virus (HIV) is one of the most threatening viral agents. This
virus infects approximately 33 million people, many of whom are unaware of their status …

[HTML][HTML] Stochastic theory of early viral infection: continuous versus burst production of virions

JE Pearson, P Krapivsky… - PLoS computational …, 2011 - journals.plos.org
Viral production from infected cells can occur continuously or in a burst that generally kills
the cell. For HIV infection, both modes of production have been suggested. Standard viral …

Stochastic analysis of pre-and postexposure prophylaxis against HIV infection

JM Conway, BP Konrad, D Coombs - SIAM Journal on Applied Mathematics, 2013 - SIAM
The events that occur following HIV exposure, preceding any detectable infection, are
difficult to study experimentally. However, there is considerable evidence that these events …

[HTML][HTML] Predicting HIV-1 transmission and antibody neutralization efficacy in vivo from stoichiometric parameters

OF Brandenberg, C Magnus, P Rusert… - PLoS …, 2017 - journals.plos.org
The potential of broadly neutralizing antibodies targeting the HIV-1 envelope trimer to
prevent HIV-1 transmission has opened new avenues for therapies and vaccines. However …

[HTML][HTML] Accurate predictions of population-level changes in sequence and structural properties of HIV-1 Env using a volatility-controlled diffusion model

O DeLeon, H Hodis, Y O'Malley, J Johnson… - PLoS …, 2017 - journals.plos.org
The envelope glycoproteins (Envs) of HIV-1 continuously evolve in the host by random
mutations and recombination events. The resulting diversity of Env variants circulating in the …

[HTML][HTML] Effect of stochasticity on coinfection dynamics of respiratory viruses

L Pinky, G Gonzalez-Parra, HM Dobrovolny - BMC bioinformatics, 2019 - Springer
Background Respiratory viral infections are a leading cause of mortality worldwide. As many
as 40% of patients hospitalized with influenza-like illness are reported to be infected with …

[HTML][HTML] On the extinction probability in models of within-host infection: the role of latency and immunity

AWC Yan, P Cao, JM McCaw - Journal of mathematical biology, 2016 - Springer
Not every exposure to virus establishes infection in the host; instead, the small amount of
initial virus could become extinct due to stochastic events. Different diseases and routes of …

Key positions of HIV-1 ENV and signatures of vaccine efficacy show gradual reduction of population founder effects at the clade and regional levels

C Han, J Johnson, R Dong, R Kandula, A Kort, M Wong… - Mbio, 2020 - Am Soc Microbiol
ABSTRACT HIV-1 group M was transmitted to humans nearly one century ago. The virus
has since evolved to form distinct clades, which spread to different regions of the world. The …

The probability of HIV infection in a new host and its reduction with microbicides

HC Tuckwell, PD Shipman, AS Perelson - Mathematical Biosciences, 2008 - Elsevier
We use a simple mathematical model to estimate the probability and its time dependence
that one or more HIV virions successfully infect target cells. For the transfer of a given …

Periodic solution of a stochastic HBV infection model with logistic hepatocyte growth

F Xie, M Shan, X Lian, W Wang - Applied Mathematics and Computation, 2017 - Elsevier
In this paper, we present a stochastic hepatitis B virus (HBV) infection model with logistic
hepatocyte growth. We show that the stochastic differential equation (SDE) HBV model has …