Background: Prader-Willi Syndrome (PWS) is a neurodevelopmental genomic imprinting
disorder with lack of expression of genes inherited from the paternal chromosome 15q11 …

Abstract Introduction Prader-Willi syndrome (PWS) is a multisystemic complex genetic
disorder caused by lack of expression of genes on the paternally inherited chromosome …

The brain is the seat of body weight homeostasis. However, our inability to control the
increasing prevalence of obesity highlights a need to look beyond canonical feeding …

Prader-Willi syndrome is characterized by severe infantile hypotonia with poor suck and
failure to thrive; hypogonadism causing genital hypoplasia and pubertal insufficiency; …

Prader–Willi syndrome (PWS) is a highly variable genetic disorder affecting multiple body
systems whose most consistent major manifestations include hypotonia with poor suck and …

Epilepsy is one of the most common neurological disorders in humans with a prevalence of
1% and a lifetime incidence of 3%. Several genes have been identified in rare autosomal …

Prader–Willi syndrome (PWS) and Angelman syndrome (AS) are two distinct neurogenetic
disorders in which imprinted genes on the proximal long arm of chromosome 15 are …

Objective: The objective of the study was to provide recommendations for the diagnosis and
management of Prader-Willi syndrome throughout the life span to guide clinical practice …

Prader-Willi syndrome is a complex disorder affecting multiple systems with many
manifestations relating to hypothalamic insufficiency. Major findings include infantile …

Patients with the 15q11. 2 BP1–BP2 microdeletion can present with developmental and
language delay, neurobehavioral disturbances and psychiatric problems. Autism, seizures …