Ischaemic stroke elicits a strong neuroinflammatory response, but the functional relevance
and therapeutic potential of neuroinflammation has only recently become apparent. In acute …

Ischaemic stroke involves the rapid onset of focal neurological dysfunction, most commonly
due to an arterial blockage in a specific region of the brain. Stroke is a leading cause of …

Nanotechnology-mediated antioxidative therapy is emerging as a novel strategy for treating
a myriad of important diseases through scavenging excessive reactive oxygen and nitrogen …

Ischemic stroke is a devastating disease and one of the leading causes of mortality
worldwide. Overproduction of reactive oxygen and nitrogen species (RONS) following …

Microglia are the main effectors in the inflammatory process of the central nervous system.
As the first line of defense, microglia play an important role in the inflammatory reaction …

While the mainstay of acute stroke treatment includes revascularization via recombinant
tissue plasminogen activator or mechanical thrombectomy, only a minority of stroke patients …

There is an urgent need for improved diagnostics and therapeutics for acute ischemic stroke.
This is the focus of numerous research projects involving in vitro studies, animal models and …

Ischemic stroke is a devastating disease with a complex pathophysiology. Animal modeling
of ischemic stroke serves as an indispensable tool first to investigate mechanisms of …

Cerebral postischemic reperfusion injury is defined as deterioration of ischemic brain tissue
that parallels and antagonizes the benefits of restoring cerebral circulation after therapeutic …

Most chronic wounds can be classified into three major types: pressure ulcers, venous
ulcers, and diabetic ulcers. The authors propose a unifying hypothesis of chronic wound …