Apolipoproteins are important structural components of plasma lipoproteins that influence
vascular biology and atherosclerotic disease pathophysiology by regulating lipoprotein …

Extracellular vesicles such as exosomes, microvesicles, apoptotic bodies, and large
oncosomes have been shown to participate in a wide variety of biological processes and are …

Material de distribuição exclusiva à classe médica. Os Arquivos Brasileiros de Cardiologia
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …

Obesity has become a major worldwide health problem. In every single country in the world,
the incidence of obesity is rising continuously and therefore, the associated morbidity …

Background High plasma levels of nonfasting triglycerides are associated with an increased
risk of ischemic cardiovascular disease. Whether lifelong low levels of nonfasting …

Background Apolipoprotein C-III (APOC3) is a key regulator of plasma triglyceride levels.
Elevated triglyceride levels are associated with a risk of adverse cardiovascular events and …

Chronic kidney disease (CKD) induces modifications in lipid and lipoprotein metabolism and
homeostasis. These modifications can promote, modulate and/or accelerate CKD and …

Abstract Background Apolipoprotein C-III (APOC3) inhibits triglyceride clearance by
reducing lipoprotein lipase–mediated hydrolysis and hepatocyte uptake of triglyceride-rich …

A long-standing association exists between elevated triglyceride levels and cardiovascular
disease*(CVD). 1, 2 However, the extent to which triglycerides directly promote CVD or …

The familial chylomicronemia syndrome is a genetic disorder characterized by severe
hypertriglyceridemia and recurrent pancreatitis due to a deficiency in lipoprotein lipase …