The development of chronic pain is considered a major complication after surgery. Basic
science research in animal models helps us understand the transition from acute to chronic …

Objectives: This review presents and discusses basic science findings and scientific
evidence generated within the last 2 decades in the field of acute postoperative pain …

Each year, more than 300 million surgeries are performed worldwide, which are often
accompanied by postoperative pain. To promote the healing process and prevent …

Nerve injury induces changes in gene transcription in dorsal root ganglion (DRG) neurons,
which may contribute to nerve injury-induced neuropathic pain. DNA methylation represses …

Practical relevance: The '2022 ISFM/AAFP Cat Friendly Veterinary Environment
Guidelines'(hereafter the 'Cat Friendly Veterinary Environment Guidelines') describe how the …

Transient receptor potential melastatin 3 (TRPM3) is a heat-activated ion channel in primary
sensory neurons of the dorsal root ganglia (DRGs). Pharmacological and genetic studies …

Voltage‐gated potassium channels (Kv) are important regulators of neuronal excitability for
its role of regulating resting membrane potential and repolarization. Recent studies show …

Chronic stress produces maladaptive pain responses, manifested as alterations in pain
processing and exacerbation of chronic pain conditions including irritable bowel syndrome …

The expression of potassium ion channel subunit 1.2 (Kv1. 2) in the dorsal root ganglion
(DRG) influences the excitability of neurons, which contributes to the induction and …

The incidence of persistent pain after cesarean deliveries (CD) varies but is much lower than
after comparable surgeries. However, with over four million deliveries annually and a rising …