Non-alcoholic fatty liver disease (NAFLD): a review of pathophysiology, clinical management and effects of weight loss

S Pouwels, N Sakran, Y Graham, A Leal, T Pintar… - BMC endocrine …, 2022 - Springer
Given the increasing prevalence of diabetes and obesity worldwide, the deleterious effects
of non-alcoholic fatty liver disease (NAFLD) are becoming a growing challenge for public …

Non-alcoholic fatty liver disease: metabolic, genetic, epigenetic and environmental risk factors

O Juanola, S Martínez-López, R Francés… - International journal of …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent causes of chronic liver
disease in the Western world, probably due to the growing prevalence of obesity, metabolic …

Cigarette smoking and liver diseases

D Marti-Aguado, A Clemente-Sanchez, R Bataller - Journal of hepatology, 2022 - Elsevier
Cigarette smoking is a preventable risk factor for premature morbidity and mortality. A history
of smoking is observed in approximately 40% of patients with liver disease, while a growing …

Non-alcoholic fatty liver disease, obesity and the metabolic syndrome

P Dietrich, C Hellerbrand - Best practice & research Clinical …, 2014 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is now recognized as the most common cause of
chronic liver disease worldwide. Its prevalence has increased to more than 30% of adults in …

[PDF][PDF] Presence of diabetes mellitus and steatosis is associated with liver stiffness in a general population: the Rotterdam study

EM Koehler, EPC Plompen, JNL Schouten… - …, 2016 - Wiley Online Library
Given that little is known about the prevalence of, and factors associated with, liver fibrosis in
the general population, we aimed to investigate this in a large, well‐characterized cohort by …

[HTML][HTML] Per-and perfluoroalkyl substances alternatives, mixtures and liver function in adults: A community-based population study in China

JJ Liu, XX Cui, YW Tan, PX Dong, YQ Ou, QQ Li… - Environment …, 2022 - Elsevier
Experimental evidence has shown that per-and polyfluoroalkyl substances (PFAS)
alternatives and mixtures may exert hepatotoxic effects in animals. However …

Lifestyle and metabolic factors for nonalcoholic fatty liver disease: Mendelian randomization study

S Yuan, J Chen, X Li, R Fan, B Arsenault, D Gill… - European journal of …, 2022 - Springer
The risk factors for nonalcoholic fatty liver disease (NAFLD) have not been clearly identified.
We conducted a Mendelian randomization (MR) study to explore this. Independent genetic …

Tobacco, alcohol use and risk of hepatocellular carcinoma and intrahepatic cholangiocarcinoma: The Liver Cancer Pooling Project

JL Petrick, PT Campbell, J Koshiol, JE Thistle… - British journal of …, 2018 - nature.com
Background While tobacco and alcohol are established risk factors for hepatocellular
carcinoma (HCC), the most common type of primary liver cancer, it is unknown whether they …

[HTML][HTML] Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic …

SMH Chan, S Selemidis, S Bozinovski… - Pharmacology & …, 2019 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …

The Apoe−/− mouse model: a suitable model to study cardiovascular and respiratory diseases in the context of cigarette smoke exposure and harm reduction

G Lo Sasso, WK Schlage, S Boué, E Veljkovic… - Journal of translational …, 2016 - Springer
Atherosclerosis-prone apolipoprotein E-deficient (Apoe−/−) mice display poor lipoprotein
clearance with subsequent accumulation of cholesterol ester-enriched particles in the blood …