Database of space life investigations and bioinformatics of microbiology in extreme environments

J Wang, T Wang, X Zeng, S Wang, Z Yu, Y Wei… - Frontiers in …, 2022 - frontiersin.org
Biological experiments performed in space crafts like space stations, space shuttles, and
recoverable satellites has enabled extensive spaceflight life investigations (SLIs). In …

Decreased biofilm formation ability of Acinetobacter baumannii after spaceflight on China's Shenzhou 11 spacecraft

X Zhao, Y Yu, X Zhang, B Huang, P Bai, C Xu… - …, 2019 - Wiley Online Library
China has prepared for construction of a space station by the early 2020s. The mission will
require astronauts to stay on the space station for at least 180 days. Microbes isolated from …

Transcriptional profiling of the mutualistic bacterium Vibrio fischeri and an hfq mutant under modeled microgravity

AA Duscher, A Conesa, M Bishop, MM Vroom… - NPJ …, 2018 - nature.com
For long-duration space missions, it is critical to maintain health-associated homeostasis
between astronauts and their microbiome. To achieve this goal it is important to more fully …

Meta-analysis of data from spaceflight transcriptome experiments does not support the idea of a common bacterial “spaceflight response”

MD Morrison, WL Nicholson - Scientific Reports, 2018 - nature.com
Several studies have been undertaken with the goal of understanding how bacterial
transcriptomes respond to the human spaceflight environment. However, these experiments …

Microbial stress: spaceflight-induced alterations in microbial virulence and infectious disease risks for the crew

CM Ott, A Crabbé, JW Wilson, J Barrila… - Stress Challenges and …, 2020 - Springer
The response of microorganisms to the spaceflight environment has tremendous
implications for the risk of infectious disease for astronauts. Seminal studies using …

Receptor tyrosine kinases (RTKs) consociate in regulatory clusters in Alzheimer's disease and type 2 diabetes

P Majumder, K Roy, S Bagh… - Molecular and Cellular …, 2019 - Springer
Alzheimer's disease (AD) and type 2 diabetes (T2D) share the common hallmark of insulin
resistance. It is conjectured that receptor tyrosine kinases (RTKs) play definitive roles in the …

A microgravity responsive synthetic genetic device in Escherichia coli

S Mukhopadhyay, S Bagh - Biosensors and Bioelectronics, 2020 - Elsevier
Bioengineering solutions to human space travel must consider microgravity as an important
component. Thus, one of the fundamental challenges of space bioengineering is to create …

Comparisons of Transcriptome Profiles from Bacillus subtilis Cells Grown in Space versus High Aspect Ratio Vessel (HARV) Clinostats Reveal a Low Degree of …

MD Morrison, WL Nicholson - Astrobiology, 2020 - liebertpub.com
Although clinostats have long been used in space microbiology studies as ground-based
analogs of spaceflight, few studies to date have systematically compared-omics data from …

Ad Meliora: Space microbial research for the benefit of humanity

YK Chen - 2021 - researchspace.auckland.ac.nz
When humans go to space, they take their microbes with them. Microbiomes benefit many
aspects of human health, but little is known about how spaceflight affects the physiology of …

Investigating the Effects of the Human Spaceflight Environment on Bacillus subtilis

MD Morrison - 2019 - search.proquest.com
Recent years have seen a renewed interest in longer manned spaceflight missions back to
the Moon and eventually Mars. In order to investigate the effect of spaceflight on bacteria …