Phosphorus, a 5A element with atomic weight of 31, comprises just over 0.6% of the
composition by weight of plants and animals. Three isotopes are available for studying …

Over the past 25 years, successive cloning of SLC34A1, SLC34A2 and SLC34A3, which
encode the sodium-dependent inorganic phosphate (Pi) cotransport proteins 2a–2c, has …

Abstract Fibroblast growth factor 23 (FGF23) is an important bone hormone that regulates
phosphate homeostasis in the kidney along with active vitamin D (1, 25 (OH) 2D3) and …

Chronic kidney disease–mineral and bone disorder (CKD–MBD) is a systemic disorder that
affects multiple organs and systems and increases the risk of morbidity and mortality in …

Fibroblast growth factor 23 (FGF 23) is mainly produced in the bone and, upon secretion,
forms a complex with a FGF receptor and coreceptor αKlotho. FGF 23 can exert several …

Abstract Fibroblast growth factor 23 (FGF23) is released primarily from
osteoblasts/osteocytes in bone. In cooperation with the transmembrane protein Klotho …

Over the past decades metformin has been the optimal first-line treatment for type 2 diabetes
mellitus (T2DM). Only in the last few years, it has become increasingly clear that metformin …

To date, the lowest protective SGLT2 inhibitor dose is unknown. We initially performed a
dose-response pilot study in normal rats. Based on the results of this pilot study we …

The hormonal vitamin D metabolite, 1, 25‐dihydroxyvitamin D [1, 25 (OH) 2D], produced in
kidney, acts in numerous end organs via the nuclear vitamin D receptor (VDR) to trigger …

Background Heart failure is a common complication of sepsis with a high mortality rate. It
has been reported that melatonin can attenuate septic injury due to various properties. On …