Dendritic cell subsets and locations
S Balan, M Saxena, N Bhardwaj - International review of cell and molecular …, 2019 - Elsevier
Dendritic cells (DCs) are a unique class of immune cells that act as a bridge between innate
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …
Single-cell transcriptomics of a human kidney allograft biopsy specimen defines a diverse inflammatory response
Background Single-cell genomics techniques are revolutionizing our ability to characterize
complex tissues. By contrast, the techniques used to analyze renal biopsy specimens have …
complex tissues. By contrast, the techniques used to analyze renal biopsy specimens have …
Dendritic cell subsets
Dendritic cells (DC) are professional antigen presenting cells comprising a variety of
subsets, as either resident or migrating cells, in lymphoid and non-lymphoid organs. In the …
subsets, as either resident or migrating cells, in lymphoid and non-lymphoid organs. In the …
The clinical application of cancer immunotherapy based on naturally circulating dendritic cells
Dendritic cells (DCs) can initiate and direct adaptive immune responses. This ability is
exploitable in DC vaccination strategies, in which DCs are educated ex vivo to present tumor …
exploitable in DC vaccination strategies, in which DCs are educated ex vivo to present tumor …
Computational prediction and validation of tumor-associated neoantigens
V Roudko, B Greenbaum, N Bhardwaj - Frontiers in Immunology, 2020 - frontiersin.org
Tumor progression is typically accompanied by an accumulation of driver and passenger
somatic mutations. A handful of those mutations occur in protein coding genes which …
somatic mutations. A handful of those mutations occur in protein coding genes which …
Human dendritic cell subsets, ontogeny, and impact on HIV infection
JW Rhodes, O Tong, AN Harman… - Frontiers in …, 2019 - frontiersin.org
Dendritic cells (DCs) play important roles in orchestrating host immunity against invading
pathogens, representing one of the first responders to infection by mucosal invaders. From …
pathogens, representing one of the first responders to infection by mucosal invaders. From …
Select hyperactivating NLRP3 ligands enhance the TH1- and TH17-inducing potential of human type 2 conventional dendritic cells
L Hatscher, CHK Lehmann, A Purbojo, C Onderka… - Science …, 2021 - science.org
The detection of microorganisms and danger signals by pattern recognition receptors on
dendritic cells (DCs) and the consequent formation of inflammasomes are pivotal for …
dendritic cells (DCs) and the consequent formation of inflammasomes are pivotal for …
Single cell transcriptomics of Atlantic salmon (Salmo salar L.) liver reveals cellular heterogeneity and immunological responses to challenge by Aeromonas …
The liver is a multitasking organ with essential functions for vertebrate health spanning
metabolism and immunity. In contrast to mammals, our understanding of liver cellular …
metabolism and immunity. In contrast to mammals, our understanding of liver cellular …
Human dendritic cell subsets undergo distinct metabolic reprogramming for immune response
Toll-like receptor (TLR) agonists induce metabolic reprogramming, which is required for
immune activation. We have investigated mechanisms that regulate metabolic adaptation …
immune activation. We have investigated mechanisms that regulate metabolic adaptation …
Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases
P Hou, Y Lin, Z Li, R Lu, Y Wang, T Tian, P Jia… - Cellular & Molecular …, 2021 - nature.com
DNA sensing and timely activation of interferon (IFN)-mediated innate immunity are crucial
for the defense against DNA virus infections and the clearance of abnormal cells. However …
for the defense against DNA virus infections and the clearance of abnormal cells. However …