Cancer immunity by tissue‐resident type 1 innate lymphoid cells and killer innate‐like T cells
Cancer progression can be restrained by tumor‐infiltrating lymphocytes in a process termed
cancer immunosurveillance. Based on how lymphocytes are activated and recruited to the …
cancer immunosurveillance. Based on how lymphocytes are activated and recruited to the …
[HTML][HTML] Hematopoietic Stem Cell Fates and the Cellular Hierarchy of Mammalian Hematopoiesis: from Transplantation Models to New Insights from in Situ Analyses
D Shaban, N Najm, L Droin, A Nijnik - Stem Cell Reviews and Reports, 2024 - Springer
Hematopoiesis is the process that generates the cells of the blood and immune system from
hematopoietic stem and progenitor cells (HSPCs) and represents the system with the most …
hematopoietic stem and progenitor cells (HSPCs) and represents the system with the most …
A mixed-effects stochastic model reveals clonal dominance in gene therapy safety studies
Background Mathematical models of haematopoiesis can provide insights on abnormal cell
expansions (clonal dominance), and in turn can guide safety monitoring in gene therapy …
expansions (clonal dominance), and in turn can guide safety monitoring in gene therapy …
Stochastic inference of clonal dominance in gene therapy studies
LD Core, MA Grzegorczyk, EC Wit - bioRxiv, 2022 - biorxiv.org
Clonal dominance is a wake-up-call for adverse events in gene therapy applications. This
phenomenon has mainly been observed as a consequence of a malignancy progression …
phenomenon has mainly been observed as a consequence of a malignancy progression …
[图书][B] Regulation of Cytotoxic Lymphocyte Effector Functions
GP Casoni - 2023 - search.proquest.com
Studies of patients with inborn errors of immunity provide an important opportunity to
understand the human immune system in a natural context. The articles in this thesis are a …
understand the human immune system in a natural context. The articles in this thesis are a …