2024 heart disease and stroke statistics: a report of US and global data from the American Heart Association

SS Martin, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke: a …

WJ Powers, AA Rabinstein, T Ackerson, OM Adeoye… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—The purpose of these guidelines is to provide an up-to-date
comprehensive set of recommendations in a single document for clinicians caring for adult …

International Atherosclerosis Society guidance for implementing best practice in the care of familial hypercholesterolaemia

GF Watts, SS Gidding, RA Hegele, FJ Raal… - Nature Reviews …, 2023 - nature.com
This contemporary, international, evidence-informed guidance aims to achieve the greatest
good for the greatest number of people with familial hypercholesterolaemia (FH) across …

2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: executive summary: a report of the …

SM Grundy, NJ Stone, AL Bailey, C Beam, KK Birtcher… - Circulation, 2019 - Am Heart Assoc
The recommendations listed in the present guideline are, whenever possible, evidence
based. An initial extensive evidence review, which included literature derived from research …

2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of …

SM Grundy, NJ Stone, AL Bailey, C Beam… - Journal of the American …, 2019 - jacc.org
The recommendations listed in the present guideline are, whenever possible, evidence
based. An initial extensive evidence review, which included literature derived from research …

Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017

M Kinoshita, K Yokote, H Arai, M Iida… - … of atherosclerosis and …, 2018 - jstage.jst.go.jp
Every 5 years, the JAS publishes guidelines for the treatment of dyslipidemia and
atherosclerosis. To date, this society has released four such guidelines. Since 2007, the JAS …

Evolocumab and clinical outcomes in patients with cardiovascular disease

MS Sabatine, RP Giugliano, AC Keech… - New England journal …, 2017 - Mass Medical Soc
Background Evolocumab is a monoclonal antibody that inhibits proprotein convertase
subtilisin–kexin type 9 (PCSK9) and lowers low-density lipoprotein (LDL) cholesterol levels …

Association between achieved low-density lipoprotein cholesterol levels and long-term cardiovascular and safety outcomes: an analysis of FOURIER-OLE

P Gaba, ML O'Donoghue, JG Park, SD Wiviott, D Atar… - Circulation, 2023 - Am Heart Assoc
Background: Low-density lipoprotein cholesterol (LDL-C) is a well-established risk factor for
atherosclerotic cardiovascular disease. However, the optimal achieved LDL-C level with …

Association between lowering LDL-C and cardiovascular risk reduction among different therapeutic interventions: a systematic review and meta-analysis

MG Silverman, BA Ference, K Im, SD Wiviott… - Jama, 2016 - jamanetwork.com
Importance The comparative clinical benefit of nonstatin therapies that reduce low-density
lipoprotein cholesterol (LDL-C) remains uncertain. Objective To evaluate the association …

Safety and efficacy of statin therapy

BB Adhyaru, TA Jacobson - Nature Reviews Cardiology, 2018 - nature.com
The 2013 ACC/AHA guidelines on blood cholesterol management were a major shift in the
delineation of the main patient groups that could benefit from statin therapy and emphasized …