Alpha-amylase is widely exploited as a drug target for preventing postprandial
hyperglycemia in diabetes and other metabolic diseases. Inhibition of this enzyme by plant …

Clove (Syzygium aromaticum) has been identified as a spice high in phytochemicals that
could be exploited in drug development. The purpose of this study is to investigate the …

HDAC8 and HDAC2 are recently reported to be overexpressed in cervical cancer. To date,
studies related to the use of dual targeted HDAC inhibitor to treat cervical cancer are not well …

One of the most pressing challenges associated with SARS treatment is the emergence of
new variants that may be transmissible, causing more severe disease or being resistant to …

This study explored the flavonoid-rich extract of beetroot (Beta vulgaris L.) for type 2
diabetes mellitus (T2D) and Alzheimer's disease (AD) dual therapy by using in vitro and …

Serine protease inhibitors (serpins) include thousands of structurally conserved proteins
playing key roles in many organisms. Mutations affecting serpins may disturb their …

Excessive fluoride exposure beyond the tolerable limit may adversely impacts brain
functionality. Betaine (BET), a trimethyl glycine, possesses antioxidant, anti-inflammatory …

Alzheimer's disease (AD) is an age-associated neurodegenerative condition marked by
amyloid plaques, synaptic dysfunction, and neuronal loss. Besides conventional medical …

Prostate cancer is a major cause of cancer-related mortality in men worldwide. The anti-
proliferative activity of Gongronema latifolium leaf extracts on some cancer cells has been …

Introduction/Objective The use of lacatomtom (LTT), a psychoactive mixture of tomtom (TT)
candies with lacasera (LC) beverage, has recently increased among young Nigerians and …