Exosomes: new molecular targets of diseases
S Samanta, S Rajasingh, N Drosos, Z Zhou… - Acta Pharmacologica …, 2018 - nature.com
Extracellular vesicles (EVs) comprise apoptotic bodies, microvesicles and exosomes, and
they perform as key regulators in cell-to-cell communication in normal as well as diseased …
they perform as key regulators in cell-to-cell communication in normal as well as diseased …
Tools for sequence-based miRNA target prediction: what to choose?
ÁL Riffo-Campos, I Riquelme… - International journal of …, 2016 - mdpi.com
MicroRNAs (miRNAs) are defined as small non-coding RNAs~ 22 nt in length. They regulate
gene expression at a post-transcriptional level through complementary base pairing with the …
gene expression at a post-transcriptional level through complementary base pairing with the …
[HTML][HTML] Isolation of cabbage exosome-like nanovesicles and investigation of their biological activities in human cells
There are extensive studies on the applications of extracellular vesicles (EVs) produced in
cell culture for therapeutic drug development. However, large quantities of EVs are needed …
cell culture for therapeutic drug development. However, large quantities of EVs are needed …
Recent advances in signal amplification strategy based on oligonucleotide and nanomaterials for microRNA detection-a review
YX Chen, KJ Huang, KX Niu - Biosensors and Bioelectronics, 2018 - Elsevier
MicroRNAs (MiRNAs) play multiple crucial regulating roles in cell which can regulate one
third of protein-coding genes. MiRNAs participate in the developmental and physiological …
third of protein-coding genes. MiRNAs participate in the developmental and physiological …
Addressing the inter‐individual variation in response to consumption of plant food bioactives: towards a better understanding of their role in healthy aging and …
Bioactive compounds in plant‐based foods have health properties that contribute to the
prevention of age‐related chronic diseases, particularly cardiometabolic disorders …
prevention of age‐related chronic diseases, particularly cardiometabolic disorders …
[HTML][HTML] Applications and developments of gene therapy drug delivery systems for genetic diseases
X Pan, H Veroniaina, N Su, K Sha, F Jiang… - Asian journal of …, 2021 - Elsevier
Genetic diseases seriously threaten human health and have always been one of the
refractory conditions facing humanity. Currently, gene therapy drugs such as siRNA, shRNA …
refractory conditions facing humanity. Currently, gene therapy drugs such as siRNA, shRNA …
MicroRNA-based therapeutics in cardiovascular disease: screening and delivery to the target
D Mellis, A Caporali - Biochemical Society Transactions, 2018 - portlandpress.com
MicroRNAs (miRNAs) are small non-coding RNAs of∼ 22 nucleotides, which have
increasingly been recognized as potent post-transcriptional regulators of gene expression …
increasingly been recognized as potent post-transcriptional regulators of gene expression …
Advances in preparation and engineering of plant-derived extracellular vesicles for nutrition intervention
C Wu, J Li, K Huang, X Tian, Y Guo, AG Skirtach… - Food Chemistry, 2024 - Elsevier
Plant-derived extracellular vesicles (PLEVs), as a type of naturally occurring lipid bilayer
membrane structure, represent an emerging delivery vehicle with immense potential due to …
membrane structure, represent an emerging delivery vehicle with immense potential due to …
microRNAs in cardiovascular disease–clinical application
Abstract microRNAs (miRNAs) are well-known, powerful regulators of gene expression, and
their potential to serve as circulating biomarkers is widely accepted. In cardiovascular …
their potential to serve as circulating biomarkers is widely accepted. In cardiovascular …
Predicting miRNA-disease associations using an ensemble learning framework with resampling method
Q Dai, Z Wang, Z Liu, X Duan, J Song… - Briefings in …, 2022 - academic.oup.com
Motivation: Accumulating evidences have indicated that microRNA (miRNA) plays a crucial
role in the pathogenesis and progression of various complex diseases. Inferring disease …
role in the pathogenesis and progression of various complex diseases. Inferring disease …