Exosomes: new molecular targets of diseases

S Samanta, S Rajasingh, N Drosos, Z Zhou… - Acta Pharmacologica …, 2018 - nature.com
Extracellular vesicles (EVs) comprise apoptotic bodies, microvesicles and exosomes, and
they perform as key regulators in cell-to-cell communication in normal as well as diseased …

Tools for sequence-based miRNA target prediction: what to choose?

ÁL Riffo-Campos, I Riquelme… - International journal of …, 2016 - mdpi.com
MicroRNAs (miRNAs) are defined as small non-coding RNAs~ 22 nt in length. They regulate
gene expression at a post-transcriptional level through complementary base pairing with the …

[HTML][HTML] Isolation of cabbage exosome-like nanovesicles and investigation of their biological activities in human cells

JY You, SJ Kang, WJ Rhee - Bioactive materials, 2021 - Elsevier
There are extensive studies on the applications of extracellular vesicles (EVs) produced in
cell culture for therapeutic drug development. However, large quantities of EVs are needed …

Recent advances in signal amplification strategy based on oligonucleotide and nanomaterials for microRNA detection-a review

YX Chen, KJ Huang, KX Niu - Biosensors and Bioelectronics, 2018 - Elsevier
MicroRNAs (MiRNAs) play multiple crucial regulating roles in cell which can regulate one
third of protein-coding genes. MiRNAs participate in the developmental and physiological …

Addressing the inter‐individual variation in response to consumption of plant food bioactives: towards a better understanding of their role in healthy aging and …

C Manach, D Milenkovic, T Van de Wiele… - Molecular nutrition & …, 2017 - Wiley Online Library
Bioactive compounds in plant‐based foods have health properties that contribute to the
prevention of age‐related chronic diseases, particularly cardiometabolic disorders …

[HTML][HTML] Applications and developments of gene therapy drug delivery systems for genetic diseases

X Pan, H Veroniaina, N Su, K Sha, F Jiang… - Asian journal of …, 2021 - Elsevier
Genetic diseases seriously threaten human health and have always been one of the
refractory conditions facing humanity. Currently, gene therapy drugs such as siRNA, shRNA …

MicroRNA-based therapeutics in cardiovascular disease: screening and delivery to the target

D Mellis, A Caporali - Biochemical Society Transactions, 2018 - portlandpress.com
MicroRNAs (miRNAs) are small non-coding RNAs of∼ 22 nucleotides, which have
increasingly been recognized as potent post-transcriptional regulators of gene expression …

Advances in preparation and engineering of plant-derived extracellular vesicles for nutrition intervention

C Wu, J Li, K Huang, X Tian, Y Guo, AG Skirtach… - Food Chemistry, 2024 - Elsevier
Plant-derived extracellular vesicles (PLEVs), as a type of naturally occurring lipid bilayer
membrane structure, represent an emerging delivery vehicle with immense potential due to …

microRNAs in cardiovascular disease–clinical application

C Schulte, M Karakas, T Zeller - Clinical Chemistry and Laboratory …, 2017 - degruyter.com
Abstract microRNAs (miRNAs) are well-known, powerful regulators of gene expression, and
their potential to serve as circulating biomarkers is widely accepted. In cardiovascular …

Predicting miRNA-disease associations using an ensemble learning framework with resampling method

Q Dai, Z Wang, Z Liu, X Duan, J Song… - Briefings in …, 2022 - academic.oup.com
Motivation: Accumulating evidences have indicated that microRNA (miRNA) plays a crucial
role in the pathogenesis and progression of various complex diseases. Inferring disease …