Templating Peptide Chemistry with Nucleic Acids: Toward Artificial Ribosomes, Cell-Specific Therapeutics, and Novel Protein-Mimetic Architectures

A Novacek, B Ugaz, N Stephanopoulos - Biomacromolecules, 2024 - ACS Publications
In biology, nanomachines like the ribosome use nucleic acid templates to synthesize
polymers in a sequence-specific, programmable fashion. Researchers have long been …

Probing Cell Membrane Tension Using DNA Framework-Encoded Vibration-Induced Emission Molecular Assemblies

C Liang, Q Huang, H Zheng, M Duan… - Journal of the …, 2024 - ACS Publications
Mechanosensitive fluorescent probes are valuable tools for detecting changes in cellular
mechanics and viscosity. While numerous mechanosensitive probes have been developed …

Modular Assembled Localized Hybridization Chain Reaction for In Situ mRNA Amplified Imaging

S Liu, J Wang, Y Chen, J Fan, B Du, R Liu, X Zhu… - Nano Letters, 2024 - ACS Publications
As a nonenzymatic DNA signal amplification technique, localized hybridization chain
reaction (LHCR) was designed to improve the limitations in response speed and low …

Toward Automated DNA Nanoprinting: Advancing the Synthesis of Covalently Branched DNA

F Zhao, D Saliba, J Asohan, HF Sleiman - Small Methods, 2024 - Wiley Online Library
Covalently branched DNA molecules are hybrid structures where a small molecule core is
covalently linked to different DNA strands. They merge the programmability of DNA …

Protein‐based 2D Nanoarchitectures Constructed by Heterochiral π‐Stacking Dimerization of Helical Foldamers

W Li, Y Ge, Z Wang, C Zhang, C Zhang… - Chemistry–An Asian …, 2024 - Wiley Online Library
In this study, we focus on the designability and controllability of the interaction interface
between secondary structures, and discover an important interface interaction between …

DNA-templated Chemical Synthesis of Proteins and Polypeptides

M Al-Amin - 2024 - keep.lib.asu.edu
Proteins are among the important macromolecules in living systems, with diverse biological
functions and properties that make them greatly interesting to study in both structure and …