Objective To evaluate the association between selective serotonin reuptake inhibitor (SSRI)
and selective serotonin and norepinephrine reuptake inhibitor (SNRI) use and risk of …

Purpose The case‐crossover design is a self‐controlled study design used to compare
exposure immediately preceding an event occurrence with exposure in earlier control …

Importance The increased use of gabapentinoids has been most pronounced in older
people who are also susceptible to hip fractures. Objective To investigate the overall …

Purpose To assess the impact of a variety of methodological parameters on the association
between six drug classes and five key adverse events in multiple databases. Methods The …

Healthcare | Free Full-Text | Antidepressants and Vertebral and Hip Risk Fracture: An
Updated Systematic Review and Meta-Analysis Next Article in Journal Burden of Mental …

Background Antidepressants are associated with adverse effects such as sedation and
hypotension, which can result in falls and fractures. Few studies have assessed the risk of …

Background Multiple medication use among older patients is reported to increase fracture
risk. But this association is unclear in different subgroups and has not been confirmed by a …

Background Concomitant use of central nervous system (CNS) medications frequently
occurs in older adults with persistent opioid use. The risks of adverse outcomes associated …

Central nervous system (CNS) agents cause fractures among the elderly, but fracture risks of
a wide range of CNS agent classes have not been analyzed in a study with the same …

The association between statin use and fractures has been investigated by several cohort
and case–control studies, with inconsistent results, but no case–crossover study has been …