Clinical trial outcomes for SLE: what we have and what we need
L Arnaud, I Parodis, H Devilliers… - Lupus Science & …, 2024 - lupus.bmj.com
The paradigm of drug approval in SLE currently relies on successful large phase III
randomised controlled trials and a set of primary, secondary and additional end points …
randomised controlled trials and a set of primary, secondary and additional end points …
An experimental test of the mutation-selection balance model for the maintenance of genetic variance in fitness components
NP Sharp, AF Agrawal - bioRxiv, 2017 - biorxiv.org
Despite decades of research, the factors that maintain genetic variation for fitness are poorly
understood. Mutation selection balance will always contribute to standing variance, but it is …
understood. Mutation selection balance will always contribute to standing variance, but it is …