Fentanyl self‐administration is accelerated by methamphetamine co‐use and results in worsened hypodopaminergia in male, but not female rats

MH Dawes, OA Ortelli, KM Holleran… - European Journal of …, 2024 - Wiley Online Library
Combined use of fentanyl and methamphetamine (FENT+ METH) has increased in recent
years and has been documented in a growing number overdose deaths each year. The …

Co-administration of naloxone and dexmedetomidine to simultaneously reverse acute effects of fentanyl and methamphetamine in rats

WR Tackett, J Yalakala, MD Hambuchen - Drug and Alcohol Dependence, 2024 - Elsevier
Background The incidence of combination methamphetamine (METH)-opioid overdose has
substantially increased in recent years. While agitation is uncommon after the naloxone …