Obesity, adipose tissue and vascular dysfunction

M Koenen, MA Hill, P Cohen, JR Sowers - Circulation research, 2021 - Am Heart Assoc
Cardiovascular diseases are the leading cause of death worldwide. Overweight and obesity
are strongly associated with comorbidities such as hypertension and insulin resistance …

[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

[HTML][HTML] Obesity and obesity-induced inflammatory disease contribute to atherosclerosis: a review of the pathophysiology and treatment of obesity

RJ Henning - American journal of cardiovascular disease, 2021 - ncbi.nlm.nih.gov
Two billion people worldwide older than 18 years of age, or approximately 30% of the world
population, are overweight or obese. In addition, more than 43 million children under the …

Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: causes and therapeutic strategies

P Manna, SK Jain - Metabolic syndrome and related disorders, 2015 - liebertpub.com
Obesity is gaining acceptance as a serious primary health burden that impairs the quality of
life because of its associated complications, including diabetes, cardiovascular diseases …

Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue

SN Saxton, BJ Clark, SB Withers… - Physiological …, 2019 - journals.physiology.org
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

[HTML][HTML] Inflammation, oxidative stress and renin angiotensin system in atherosclerosis

K Husain, W Hernandez, RA Ansari… - World journal of …, 2015 - ncbi.nlm.nih.gov
Atherosclerosis is a chronic inflammatory disease associated with cardiovascular
dysfunction including myocardial infarction, unstable angina, sudden cardiac death, stroke …

[HTML][HTML] Resistin: A reappraisal

E Acquarone, F Monacelli, R Borghi, A Nencioni… - Mechanisms of ageing …, 2019 - Elsevier
From a biological point of view, aging can be considered a progressive inability of an
organism to react to stress, maintain homeostasis, and survive unfavourable changes during …

[HTML][HTML] Diabetes and restenosis

S Wilson, P Mone, U Kansakar, SS Jankauskas… - Cardiovascular …, 2022 - Springer
Restenosis, defined as the re-narrowing of an arterial lumen after revascularization,
represents an increasingly important issue in clinical practice. Indeed, as the number of stent …

Resistin: functional roles and therapeutic considerations for cardiovascular disease

MS Jamaluddin, SM Weakley, Q Yao… - British journal of …, 2012 - Wiley Online Library
Resistin, originally described as an adipocyte‐specific hormone, has been suggested to be
an important link between obesity, insulin resistance and diabetes. Although its expression …

Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action

RZ Yang, MJ Lee, H Hu, J Pray… - American journal …, 2006 - journals.physiology.org
Central (visceral) obesity is more closely associated with insulin resistance, type 2 diabetes,
and cardiovascular disease than is peripheral [subcutaneous (sc)] obesity, but the …