This review presents an overview of the dynamically developing field of mass spectrometry‐
based metabolomics. Metabolomics aims at the comprehensive and quantitative analysis of …

The collection of whole blood samples on paper, known as dried blood spot (DBS), dates
back to the early 1960s in newborn screening for inherited metabolic disorders. DBS offers a …

Aging is characterized by a general decline in cellular function, which ultimately will affect
whole body homeostasis. Although DNA damage and oxidative stress all contribute to …

Dried blood spots (DBS) typically consist in the deposition of small volumes of capillary
blood onto dedicated paper cards. Comparatively to whole blood or plasma samples, their …

Proteins are major targets for oxidative damage due to their abundance and rapid rates of
reaction with a wide range of radicals and excited state species, such as singlet oxygen …

Compared to soy, whey protein is higher in leucine, absorbed quicker and results in a more
pronounced increase in muscle protein synthesis. Objective: To determine whether …

Background Amino acidopathies are a class of inborn errors of metabolism (IEM) that can be
diagnosed by analysis of amino acids (AA) in plasma. Current strategies for AA analysis …

Many photosynthetic organisms employ a CO2 concentrating mechanism (CCM) to increase
the rate of CO2 fixation via the Calvin cycle. CCMs catalyze≈ 50% of global photosynthesis …

Nitric oxide (. NO)-derived reactive species nitrate unsaturated fatty acids, yielding
nitroalkene derivatives, including the clinically abundant nitrated oleic and linoleic acids …

Fragmentation reactions of protonated α-amino acids (AAs) were studied previously using
tandem mass spectrometry (MS/MS) of unit mass resolution. Isobaric fragmentation products …