Genome-and transcriptome-wide association studies of 386,000 Asian and European-ancestry women provide new insights into breast cancer genetics
By combining data from 160,500 individuals with breast cancer and 226,196 controls of
Asian and European ancestry, we conducted genome-and transcriptome-wide association …
Asian and European ancestry, we conducted genome-and transcriptome-wide association …
Mammography screening is associated with more favourable breast cancer tumour characteristics and better overall survival: case-only analysis of 3739 Asian breast …
Background Early detection of breast cancer (BC) through mammography screening (MAM)
is known to reduce mortality. We examined the differential effect that mammography has on …
is known to reduce mortality. We examined the differential effect that mammography has on …
Ethnic predisposition, risk factors and breast cancer presentation; a 10-year data. Single centered prospective cohort study from Karachi
N Sultan, SA Memon, M Mooghal, S Wali… - Annals of Medicine …, 2022 - journals.lww.com
Background: Breast cancer, a leading cause of mortality among females, has been the
center of research for many decades. Work is in progress to advance the research …
center of research for many decades. Work is in progress to advance the research …
[HTML][HTML] Attitudes and barriers to mammography screening in Singaporean women through the eyes of their adult children: A focus group study
JJK Liow, ZL Lim, PJ Ho, SA Goh, S Murali… - … -Qualitative Research in …, 2022 - Elsevier
Early detection of breast cancers is known to save lives, yet less than 40% of Singaporean
women participate in routine mammography screening. While previous research to …
women participate in routine mammography screening. While previous research to …
Germline breast cancer susceptibility genes, tumor characteristics, and survival
Background Mutations in certain genes are known to increase breast cancer risk. We study
the relevance of rare protein-truncating variants (PTVs) that may result in loss-of-function in …
the relevance of rare protein-truncating variants (PTVs) that may result in loss-of-function in …
Characterizing the Relationship between Expression Quantitative Trait Loci (eQTLs), DNA Methylation Quantitative Trait Loci (mQTLs), and Breast Cancer Risk …
Simple Summary In the last few decades, studies have found many common genetic
variants linked to breast cancer. Most of these variants are in non-coding regions or regions …
variants linked to breast cancer. Most of these variants are in non-coding regions or regions …
How Asian Breast Cancer Patients Experience Unequal Incidence of Chemotherapy Side Effects: A Look at Ethnic Disparities in Febrile Neutropenia Rates
Simple Summary In this two-part study, we assessed the risk factors associated with FN. On
top of commonly associated risk factors such as age and body mass index, we found that …
top of commonly associated risk factors such as age and body mass index, we found that …
Long-Term Oncologic Outcomes of Omitting Axillary Surgery in Breast Cancer Patients with Chest Wall Recurrence after Mastectomy
GH Lim, VS Alcantara, JC Allen Jr, SE Saffari… - …, 2024 - pmc.ncbi.nlm.nih.gov
Simple Summary The management of the axilla for post-mastectomy breast cancer patients
who develop a chest wall recurrence (CWR) remains to be established. This study aimed to …
who develop a chest wall recurrence (CWR) remains to be established. This study aimed to …
Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification
Background Family history, and genetic and non-genetic risk factors can stratify women
according to their individual risk of developing breast cancer. The extent of overlap between …
according to their individual risk of developing breast cancer. The extent of overlap between …
Alterations to DNA methylation patterns induced by chemotherapy treatment are associated with negative impacts on the olfactory pathway
Background Exposure to cytotoxic chemotherapy treatment may alter DNA methylation
(DNAm) in breast cancer patients. Methods We performed DNAm analysis in 125 breast …
(DNAm) in breast cancer patients. Methods We performed DNAm analysis in 125 breast …