Oxidative stress and male infertility—a clinical perspective

K Tremellen - Human reproduction update, 2008 - academic.oup.com
Oxidative stress occurs when the production of potentially destructive reactive oxygen
species (ROS) exceeds the bodies own natural antioxidant defenses, resulting in cellular …

diagnosis and impact of sperm DNA alterations in assisted reproduction

L Simon, BR Emery, DT Carrell - … Practice & Research Clinical Obstetrics & …, 2017 - Elsevier
Highlights•Sperm nuclear and chromatin abnormalities are common among infertile men
and are known to influence natural reproduction.•The haploid paternal genome provides the …

Effects of cryopreservation on sperm parameters and ultrastructural morphology of human spermatozoa

S Ozkavukcu, E Erdemli, A Isik, D Oztuna… - Journal of assisted …, 2008 - Springer
Purpose Cryopreservation of sperm is a widely used technique to maintain and protect the
fertility in various occasions such as infertility and malignancy treatments. This study aims to …

Oxidative stress status and sperm DNA fragmentation in fertile and infertile men

M Dorostghoal, SR Kazeminejad, N Shahbazian… - Andrologia, 2017 - Wiley Online Library
Evidence suggests that disturbing the balance between reactive oxygen species levels and
antioxidant contents in seminal plasma leads to oxidative stress resulting in male infertility …

DNA fragmentation of sperm: a radical examination of the contribution of oxidative stress and age in 16 945 semen samples

DA Vaughan, E Tirado, D Garcia, V Datta… - Human …, 2020 - academic.oup.com
STUDY QUESTION What is the relationship between sperm DNA fragmentation and
oxidative stress (OS) with increasing male age? SUMMARY ANSWER Sperm DNA …

[HTML][HTML] Correlation of sperm parameters with semen lipid peroxidation and total antioxidants levels in astheno-and oligoasheno-teratospermic men

AH Colagar, F Karimi, SGA Jorsaraei - Iranian Red Crescent …, 2013 - ncbi.nlm.nih.gov
Background Sperm dysfunction caused by reactive oxygen species (ROSs) is one of the
major causes of infertility in men, which leads to, lipid peroxidation (LPO) and the formation …

Sperm DNA fragmentation: consequences for reproduction

L Simon, B Emery, DT Carrell - Genetic Damage in Human Spermatozoa, 2019 - Springer
DNA fragmentation, or the accumulation of single-and double-strand DNA breaks, is a
common property of sperm, and an increase in the level of sperm DNA fragmentation is …

A comparative study of oxidative DNA damage in mammalian spermatozoa

LE Bennetts, RJ Aitken - Molecular Reproduction and …, 2005 - Wiley Online Library
Alkaline gel electrophoresis, pulsed field gel electrophoresis, and quantitative PCR
analyses (QPCR) of the nuclear (nDNA) and mitochondrial (mtDNA) genomes were used to …

[HTML][HTML] Levels of oxidative stress biomarkers in seminal plasma and their relationship with seminal parameters

A Khosrowbeygi, N Zarghami - BMC clinical pathology, 2007 - Springer
Background There is growing evidence that damage to spermatozoa by reactive oxygen
species (ROS) play a key role in male infertility. The aim of the present study was to assess …

[HTML][HTML] The total antioxidant power of semen and its correlation with the fertility potential of human male subjects

PP Pahune, AR Choudhari… - Journal of clinical and …, 2013 - ncbi.nlm.nih.gov
Background: There are growing evidences that the damage which is caused to the
spermatozoa by the Reactive Oxygen Species (ROS) plays a key role in the male infertility …