Ultrasound contrast imaging: Fundamentals and emerging technology

H Yusefi, B Helfield - Frontiers in Physics, 2022 - frontiersin.org
The development of microbubble contrast agents has broadened the scope of medical
ultrasound imaging. Along with dedicated imaging techniques, these agents provide …

A review of phospholipid encapsulated ultrasound contrast agent microbubble physics

B Helfield - Ultrasound in medicine & biology, 2019 - Elsevier
Ultrasound contrast agent microbubbles have expanded the utility of biomedical ultrasound
from anatomic imaging to the assessment of microvascular blood flow characteristics and …

Nonlinear dynamics of acoustic bubbles excited by their pressure-dependent subharmonic resonance frequency: influence of the pressure amplitude, frequency …

AJ Sojahrood, R Earl, H Haghi, Q Li, TM Porter… - Nonlinear …, 2021 - Springer
Nonlinear behavior of bubbles, and most importantly 1 2 1 2-order subharmonics (SH), are
used to increase the contrast-to-tissue ratio (CTR) in diagnostic ultrasound (US) and to …

Classification of the major nonlinear regimes of oscillations, oscillation properties, and mechanisms of wave energy dissipation in the nonlinear oscillations of coated …

AJ Sojahrood, H Haghi, R Karshafian, MC Kolios - Physics of Fluids, 2021 - pubs.aip.org
Acoustic waves are dissipated when they pass through bubbly media. Dissipation by
bubbles takes place through thermal damping (Td), radiation damping (Rd), and damping …

Nonlinear resonance behavior and linear shell estimates for Definity™ and MicroMarker™ assessed with acoustic microbubble spectroscopy

BL Helfield, DE Goertz - The Journal of the Acoustical Society of …, 2013 - pubs.aip.org
There is a growing interest in microbubble based ultrasound contrast imaging applications
in the 5–15 MHz range. In this study, individual microbubbles were insonified at low …

Targeted ultrasound contrast agents for ultrasound molecular imaging and therapy

T van Rooij, V Daeichin, I Skachkov… - International journal …, 2015 - Taylor & Francis
Ultrasound contrast agents (UCAs) are used routinely in the clinic to enhance contrast in
ultrasonography. More recently, UCAs have been functionalised by conjugating ligands to …

The effect of boundary proximity on the response of individual ultrasound contrast agent microbubbles

BL Helfield, BYC Leung, DE Goertz - Physics in Medicine & …, 2014 - iopscience.iop.org
The effect of boundary proximity on ultrasound contrast agent microbubble emissions can
play an important role in the context of both targeted microbubble imaging and contrast …

The role of microbubble echo phase lag in multipulse contrast-enhanced ultrasound imaging

C Tremblay-Darveau, PS Sheeran… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
In this paper, we assess the importance of microbubble shell composition for contrast-
enhanced imaging sequences commonly used on clinical scanners. While the gas core …

Scaling of the viscoelastic shell properties of phospholipid encapsulated microbubbles with ultrasound frequency

BL Helfield, BYC Leung, X Huo, DE Goertz - Ultrasonics, 2014 - Elsevier
Phospholipid encapsulated microbubbles are widely employed as clinical diagnostic
ultrasound contrast agents in the 1–5 MHz range, and are increasingly employed at higher …

[PDF][PDF] Proceedings of Meetings on Acoustics

N Xiang - Proceedings of Meetings on Acoustics, 2009 - asa.scitation.org
Many acousticians believe publishing in reputable, archival, acoustic journals is crucial to
disseminate their research. The Journal of the Acoustical Society of America (JASA) is one …