Clinical detection, diagnosis and treatment of morphological abnormalities of sperm flagella: A review of literature

J Wang, W Wang, L Shen, A Zheng, Q Meng, H Li… - Frontiers in …, 2022 - frontiersin.org
Sperm carries male genetic information, and flagella help move the sperm to reach oocytes.
When the ultrastructure of the flagella is abnormal, the sperm is unable to reach the oocyte …

Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins

S Kubo, CS Black, E Joachimiak, SK Yang… - Nature …, 2023 - nature.com
Cilia are ubiquitous eukaryotic organelles responsible for cellular motility and sensory
functions. The ciliary axoneme is a microtubule-based cytoskeleton consisting of two central …

PCD Genes—From Patients to Model Organisms and Back to Humans

M Niziolek, M Bicka, A Osinka, Z Samsel… - International journal of …, 2022 - mdpi.com
Primary ciliary dyskinesia (PCD) is a hereditary genetic disorder caused by the lack of motile
cilia or the assembxly of dysfunctional ones. This rare human disease affects 1 out of 10,000 …

Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism

A Ghanaeian, S Majhi, CL McCafferty, B Nami… - Nature …, 2023 - nature.com
Cilia are hairlike protrusions that project from the surface of eukaryotic cells and play key
roles in cell signaling and motility. Ciliary motility is regulated by the conserved nexin-dynein …

ADGB variants cause asthenozoospermia and male infertility

R Qu, Z Zhang, L Wu, Q Li, J Mu, L Zhao, Z Yan… - Human Genetics, 2023 - Springer
Asthenozoospermia is one of the main factors leading to male infertility, but the genetic
mechanisms have not been fully elucidated. Variants in the androglobin (ADGB) gene were …

Intracellular connections between basal bodies promote the coordinated behavior of motile cilia

AWJ Soh, LG Woodhams, AD Junker… - Molecular biology of …, 2022 - Am Soc Cell Biol
Hydrodynamic flow produced by multiciliated cells is critical for fluid circulation and cell
motility. Hundreds of cilia beat with metachronal synchrony for fluid flow. Cilia-driven fluid …

Associations between circulating IGF-1 concentrations, disease status and the leukocyte transcriptome in early lactation dairy cows

DC Wathes, F Becker, L Buggiotti, MA Crowe, C Ferris… - Ruminants, 2021 - mdpi.com
Peripartum dairy cows commonly experience negative energy balance (EB) and
immunosuppression together with high incidences of infectious and metabolic disease. This …

Recent advances in ciliate biology

RA Howard-Till, UP Kar, AS Fabritius… - Annual Review of Cell …, 2022 - annualreviews.org
Ciliates are a diverse group of unicellular eukaryotes that vary widely in size, shape, body
plan, and ecological niche. Here, we review recent research advances achieved with ciliate …

Cfap91-Dependent Stability of the RS2 and RS3 Base Proteins and Adjacent Inner Dynein Arms in Tetrahymena Cilia

M Bicka, E Joachimiak, P Urbanska, A Osinka… - Cells, 2022 - mdpi.com
Motile cilia and eukaryotic flagella are specific cell protrusions that are conserved from
protists to humans. They are supported by a skeleton composed of uniquely organized …

A‐kinase anchoring proteins are enriched in the central pair microtubules of motile cilia in Chlamydomonas reinhardtii

VG Rao, AA Shendge, PP D'Gama, EAF Martis… - FEBS …, 2024 - Wiley Online Library
Cilia are microtubule‐based sensory organelles present in a number of eukaryotic cells.
Mutations in the genes encoding ciliary proteins cause ciliopathies in humans. A‐kinase …