[HTML][HTML] Polycystic ovary syndrome and mitochondrial dysfunction
J Zhang, Y Bao, X Zhou, L Zheng - Reproductive Biology and …, 2019 - Springer
Polycystic ovary syndrome (PCOS) is a prevalent hormonal disorder of premenopausal
women worldwide and is characterized by reproductive, endocrine, and metabolic …
women worldwide and is characterized by reproductive, endocrine, and metabolic …
Physiological and molecular determinants of embryo implantation
S Zhang, H Lin, S Kong, S Wang, H Wang… - Molecular aspects of …, 2013 - Elsevier
Embryo implantation involves the intimate interaction between an implantation-competent
blastocyst and a receptive uterus, which occurs in a limited time period known as the …
blastocyst and a receptive uterus, which occurs in a limited time period known as the …
[HTML][HTML] Nuclear localization of mitochondrial TCA cycle enzymes as a critical step in mammalian zygotic genome activation
R Nagaraj, MS Sharpley, F Chi, D Braas, Y Zhou… - Cell, 2017 - cell.com
Transcriptional control requires epigenetic changes directed by mitochondrial tricarboxylic
acid (TCA) cycle metabolites. In the mouse embryo, global epigenetic changes occur during …
acid (TCA) cycle metabolites. In the mouse embryo, global epigenetic changes occur during …
Mitochondrial function in the human oocyte and embryo and their role in developmental competence
J Van Blerkom - Mitochondrion, 2011 - Elsevier
The role of mitochondria as a nexus of developmental regulation in mammalian oogenesis
and early embryogenesis is emerging from basic research in model species and from …
and early embryogenesis is emerging from basic research in model species and from …
[HTML][HTML] Maternal diet-induced obesity alters mitochondrial activity and redox status in mouse oocytes and zygotes
The negative impact of obesity on reproductive success is well documented but the stages at
which development of the conceptus is compromised and the mechanisms responsible for …
which development of the conceptus is compromised and the mechanisms responsible for …
Beta-oxidation is essential for mouse oocyte developmental competence and early embryo development
KR Dunning, K Cashman, DL Russell… - Biology of …, 2010 - academic.oup.com
Oocyte and embryo metabolism are closely linked with their subsequent developmental
capacity. Lipids are a potent source of cellular energy, yet little is known about lipid …
capacity. Lipids are a potent source of cellular energy, yet little is known about lipid …
The role of mitochondrial function in the oocyte and embryo
Mitochondria have long been known to be the powerhouses of the cell but they also
contribute to redox and Ca 2+ homeostasis, provide intermediary metabolites and store …
contribute to redox and Ca 2+ homeostasis, provide intermediary metabolites and store …
Synergistic effect of a novel chitosan/silica nanocomposites-based formulation against gray mold of table grapes and its possible mode of action
Ecofriendly nanostructured materials have been proposed as promising alternative control
means to prevent plant diseases. Chitosan nanoparticles (CN), silica nanoparticles (SN) and …
means to prevent plant diseases. Chitosan nanoparticles (CN), silica nanoparticles (SN) and …
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions
R Tomasini, K Tsuchihara, M Wilhelm… - Genes & …, 2008 - genesdev.cshlp.org
The Trp53 gene family member Trp73 encodes two major groups of protein isoforms, TAp73
and ΔNp73, with opposing pro-and anti-apoptotic functions; consequently, their relative ratio …
and ΔNp73, with opposing pro-and anti-apoptotic functions; consequently, their relative ratio …
[HTML][HTML] Mitochondria in human oogenesis and preimplantation embryogenesis: engines of metabolism, ionic regulation and developmental competence
J Van Blerkom - Reproduction, 2004 - rep.bioscientifica.com
Mitochondria are the most abundant organelles in the mammalian oocyte and early embryo.
While their role in ATP production has long been known, only recently has their contribution …
While their role in ATP production has long been known, only recently has their contribution …