[HTML][HTML] Polycystic ovary syndrome and mitochondrial dysfunction

J Zhang, Y Bao, X Zhou, L Zheng - Reproductive Biology and …, 2019 - Springer
Polycystic ovary syndrome (PCOS) is a prevalent hormonal disorder of premenopausal
women worldwide and is characterized by reproductive, endocrine, and metabolic …

Physiological and molecular determinants of embryo implantation

S Zhang, H Lin, S Kong, S Wang, H Wang… - Molecular aspects of …, 2013 - Elsevier
Embryo implantation involves the intimate interaction between an implantation-competent
blastocyst and a receptive uterus, which occurs in a limited time period known as the …

[HTML][HTML] Nuclear localization of mitochondrial TCA cycle enzymes as a critical step in mammalian zygotic genome activation

R Nagaraj, MS Sharpley, F Chi, D Braas, Y Zhou… - Cell, 2017 - cell.com
Transcriptional control requires epigenetic changes directed by mitochondrial tricarboxylic
acid (TCA) cycle metabolites. In the mouse embryo, global epigenetic changes occur during …

Mitochondrial function in the human oocyte and embryo and their role in developmental competence

J Van Blerkom - Mitochondrion, 2011 - Elsevier
The role of mitochondria as a nexus of developmental regulation in mammalian oogenesis
and early embryogenesis is emerging from basic research in model species and from …

[HTML][HTML] Maternal diet-induced obesity alters mitochondrial activity and redox status in mouse oocytes and zygotes

N Igosheva, AY Abramov, L Poston, JJ Eckert… - PloS one, 2010 - journals.plos.org
The negative impact of obesity on reproductive success is well documented but the stages at
which development of the conceptus is compromised and the mechanisms responsible for …

Beta-oxidation is essential for mouse oocyte developmental competence and early embryo development

KR Dunning, K Cashman, DL Russell… - Biology of …, 2010 - academic.oup.com
Oocyte and embryo metabolism are closely linked with their subsequent developmental
capacity. Lipids are a potent source of cellular energy, yet little is known about lipid …

The role of mitochondrial function in the oocyte and embryo

R Dumollard, M Duchen, J Carroll - Current topics in developmental …, 2007 - Elsevier
Mitochondria have long been known to be the powerhouses of the cell but they also
contribute to redox and Ca 2+ homeostasis, provide intermediary metabolites and store …

Synergistic effect of a novel chitosan/silica nanocomposites-based formulation against gray mold of table grapes and its possible mode of action

K Youssef, AG de Oliveira, CA Tischer, I Hussain… - International journal of …, 2019 - Elsevier
Ecofriendly nanostructured materials have been proposed as promising alternative control
means to prevent plant diseases. Chitosan nanoparticles (CN), silica nanoparticles (SN) and …

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

R Tomasini, K Tsuchihara, M Wilhelm… - Genes & …, 2008 - genesdev.cshlp.org
The Trp53 gene family member Trp73 encodes two major groups of protein isoforms, TAp73
and ΔNp73, with opposing pro-and anti-apoptotic functions; consequently, their relative ratio …

[HTML][HTML] Mitochondria in human oogenesis and preimplantation embryogenesis: engines of metabolism, ionic regulation and developmental competence

J Van Blerkom - Reproduction, 2004 - rep.bioscientifica.com
Mitochondria are the most abundant organelles in the mammalian oocyte and early embryo.
While their role in ATP production has long been known, only recently has their contribution …