The classic definition of precocious sexual maturation is the development of secondary
sexual characteristics before 8 years of age in girls and before 9 years of age in boys. It is …

Background The gonadotropin-releasing hormone (GnRH) stimulation test is the benchmark
for diagnosing precocious puberty (PP). However, it is invasive, time-consuming, costly, and …

Objectives Data on the predictive values of parameters included in the diagnostic work-up
for precocious puberty (PP) remain limited. We detected the diagnostic value of basal sex …

The gonadotropin-releasing hormone (GnRH) stimulation test is a valuable tool in
diagnosing and differentiating causes of early pubertal occurrences. Utility of the test can be …

Sexual precocity refers to the appearance of physical and hormonal signs of pubertal
development at an earlier age. It may be considered as the expression of secondary sexual …

The gonadotropin-releasing hormone (GnRH) stimulation test is the gold standard for
differentiating central precocious puberty (CPP) from exaggerated thelarche (ET). Because …

The uterine artery pulsatility index (PI) assessed by Doppler ultrasound reflects the
impedance to the blood flow in the vessel distal to the sampling point. We aimed to assess …

OBJECTIVE. The purpose of this study is to validate the accuracy of pelvic ultrasound (US)
with the evaluation of uterine artery pulsatility index (PI) to exclude female precocious …

Background: Differentiation of patients with central precocious puberty (CPP) from healthy
individuals and patients with CPP-like conditions [isolated premature thelarche (IPT) and …

Purpose To identify cut-off for basal LH levels and for pelvic ultrasound uterine and ovarian
parameters indicating an Hypotalamic–Pituitary–Gonadal (HPG) axis activation as …