Advances in respiratory physiology in mouse models of experimental asthma
Recent advances in mouse models of experimental asthma coupled with vast improvements
in systems that assess respiratory physiology have considerably increased the accuracy and …
in systems that assess respiratory physiology have considerably increased the accuracy and …
Aging-related mechanisms contribute to corticosteroid insensitivity in elderly asthma
ML Ford, A Ruwanpathirana, BW Lewis… - International journal of …, 2023 - mdpi.com
Asthma in elderly populations is an increasing health problem that is accompanied by
diminished lung function and frequent exacerbations. As potent anti-inflammatory drugs …
diminished lung function and frequent exacerbations. As potent anti-inflammatory drugs …
Probiotic Bifidobacterium longum subsp. longum Protects against Cigarette Smoke-Induced Inflammation in Mice
Bifidobacterium are prominent gut commensals that produce the short-chain fatty acid
(SCFA) acetate, and they are often used as probiotics. Connections between the gut and the …
(SCFA) acetate, and they are often used as probiotics. Connections between the gut and the …
Isthmin-1 attenuates allergic Asthma by stimulating adiponectin expression and alveolar macrophage efferocytosis in mice
JH Tee, U Vijayakumar, M Shanmugasundaram… - Respiratory …, 2023 - Springer
Background Allergic asthma is a common respiratory disease that significantly impacts
human health. Through in silico analysis of human lung RNASeq, we found that asthmatic …
human health. Through in silico analysis of human lung RNASeq, we found that asthmatic …
Understanding Comorbidities of Respiratory Models as Novel Platforms for Drug Discovery
SN De Luca, A Gunatilaka… - ACS Pharmacology & …, 2024 - ACS Publications
Chronic respiratory diseases affect over 450 million people worldwide and result in 4 million
deaths per year. The majority of lung diseases are treated with drugs delivered directly to the …
deaths per year. The majority of lung diseases are treated with drugs delivered directly to the …
Faecal microbial transfer and complex carbohydrates mediate protection against COPD
Objective Chronic obstructive pulmonary disease (COPD) is a major cause of global illness
and death, most commonly caused by cigarette smoke. The mechanisms of pathogenesis …
and death, most commonly caused by cigarette smoke. The mechanisms of pathogenesis …
Meta-Analysis and DIA-MS-Based Proteomic Investigation of COPD Patients and Asymptomatic Smokers in the Indian Population
G Sharma, DP Gupta, K Ganguly… - Journal of Proteome …, 2024 - ACS Publications
Chronic obstructive pulmonary disease (COPD) is India's second largest cause of death and
is largely caused by smoking. Asymptomatic smokers develop COPD due to genetic …
is largely caused by smoking. Asymptomatic smokers develop COPD due to genetic …
Maternal thirdhand exposure to e-cigarette vapor alters lung and bone marrow immune cell responses in offspring in the absence or presence of influenza infection
C Donovan, AE Thorpe, R Yarak… - … of Physiology-Lung …, 2024 - journals.physiology.org
There is increasing evidence that thirdhand exposure to e-cigarette vapor (e-vapor) can
have detrimental effects on the lungs. However, whether maternal exposure during …
have detrimental effects on the lungs. However, whether maternal exposure during …
Airway and parenchyma transcriptomics in a house dust mite model of experimental asthma
Lung transcriptomics studies in asthma have provided valuable information in the whole
lung context, however, deciphering the individual contributions of the airway and …
lung context, however, deciphering the individual contributions of the airway and …
Endotypes of Paediatric Cough—Do They Exist and Finding New Techniques to Improve Clinical Outcomes
HE O'Farrell, HC Kok, S Goel, AB Chang… - Journal of Clinical …, 2024 - mdpi.com
Chronic cough is a common symptom of many childhood lung conditions. Given the
phenotypic heterogeneity of chronic cough, better characterization through endotyping is …
phenotypic heterogeneity of chronic cough, better characterization through endotyping is …