Unveiling genetic variants for age-related sarcopenia by conducting a genome-wide association study on Korean cohorts
Sarcopenia is an age-related disorder characterised by a progressive decrease in skeletal
muscle mass. As the genetic biomarkers for sarcopenia are not yet well characterised, this …
muscle mass. As the genetic biomarkers for sarcopenia are not yet well characterised, this …
Genome-wide identification of loci associated with growth in rainbow trout
Background Growth is a major economic production trait in aquaculture. Improvements in
growth performance will reduce time and cost for fish to reach market size. However, genes …
growth performance will reduce time and cost for fish to reach market size. However, genes …
Alternative diagnosis of epilepsy in children without epileptiform discharges using deep convolutional neural networks
LC Lin, CS Ouyang, RC Wu, RC Yang… - International journal of …, 2020 - World Scientific
Numerous nonepileptic paroxysmal events, such as syncope and psychogenic nonepileptic
seizures, may imitate seizures and impede diagnosis. Misdiagnosis can lead to …
seizures, may imitate seizures and impede diagnosis. Misdiagnosis can lead to …
Impact of hyperuricemia on CKD risk beyond genetic predisposition in a population-based cohort study
Y Kim, J Jo, Y Ji, E Bae, K Lee, JH Paek, K Jin… - Scientific Reports, 2024 - nature.com
The bidirectional effect of hyperuricemia on chronic kidney disease (CKD) underscores the
importance of hyperuricemia as a risk factor for CKD. We evaluated the effect of …
importance of hyperuricemia as a risk factor for CKD. We evaluated the effect of …
Identification of genetic variants associated with diabetic kidney disease in multiple Korean cohorts via a genome-wide association study mega-analysis
Background The pathogenesis of diabetic kidney disease (DKD) is complex, involving
metabolic and hemodynamic factors. Although DKD has been established as a heritable …
metabolic and hemodynamic factors. Although DKD has been established as a heritable …
Effects of polygenic risk score and sodium and potassium intake on hypertension in Asians: A nationwide prospective cohort study
E Bae, Y Ji, J Jo, Y Kim, JP Lee, S Won, J Lee - Hypertension Research, 2024 - nature.com
Genetic factors, lifestyle, and diet have been shown to play important roles in the
development of hypertension. Increased salt intake is an important risk factor for …
development of hypertension. Increased salt intake is an important risk factor for …
A missense variant in SHARPIN mediates Alzheimer's disease-specific brain damages
Established genetic risk factors for Alzheimer's disease (AD) account for only a portion of AD
heritability. The aim of this study was to identify novel associations between genetic variants …
heritability. The aim of this study was to identify novel associations between genetic variants …
[HTML][HTML] Associations between plasma metabolites and heavy metal exposure in residents of environmentally polluted areas
Heavy metals are commonly released into the environment through industrial processes
such as mining and refining. The rapid industrialization that occurred in South Korea during …
such as mining and refining. The rapid industrialization that occurred in South Korea during …
Genome-wide association study implicates the role of TBXAS1 in the pathogenesis of depressive symptoms among the Korean population
Although depression is an emerging disorder affecting many people worldwide, most
genetic studies have been performed in European descent populations. Herein, a genome …
genetic studies have been performed in European descent populations. Herein, a genome …
Integrated genetic and epigenetic analyses uncover MSI2 association with allergic inflammation
Background The relationship between allergic and eosinophilic inflammation, either
systemic or local, in allergic diseases remains unclear. Objective We performed combined …
systemic or local, in allergic diseases remains unclear. Objective We performed combined …