[HTML][HTML] The Pivotal Role of Preclinical Animal Models in Anti-Cancer Drug Discovery and Personalized Cancer Therapy Strategies

H Guo, X Xu, J Zhang, Y Du, X Yang, Z He, L Zhao… - Pharmaceuticals, 2024 - mdpi.com
The establishment and utilization of preclinical animal models constitute a pivotal aspect
across all facets of cancer research, indispensably contributing to the comprehension of …

Thymoquinone: A Promising Therapeutic Agent for the Treatment of Colorectal Cancer

N Kurowska, M Madej, B Strzalka-Mrozik - Current Issues in Molecular …, 2023 - mdpi.com
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers and is
responsible for approximately one million deaths each year. The current standard of care is …

Azadirachtin Attenuates Carcinogen Benzo (a) Pyrene-Induced DNA Damage, Cell Cycle Arrest, Apoptosis, Inflammatory, Metabolic, and Oxidative Stress in HepG2 …

A John, H Raza - Antioxidants, 2023 - mdpi.com
Azadirachtin (AZD), a limonoid from the versatile, tropical neem tree (Azadirachta indica), is
well known for its many medicinal, and pharmacological effects. Its effects as an anti-oxidant …

High-frequency ultrasound-assisted drug delivery of chia, cress, and flax conjugated hematite iron oxide nanoparticle for sono-photodynamic lung cancer treatment in …

SA Abd El-Kaream, DFM Zedan, HM Mohamed… - Cancer …, 2024 - Springer
Background Sono-photodynamic therapy (SPDT), which combines photodynamic (PDT) and
sonodynamic (SDT) therapies with sensitizers, offers new avenues for cancer treatment …

Histopathologic and Antioxidant Regulatory Effects of Different Doses of Thymoquinone Against 2, 4, 6‐Trinitrobenzene Sulfonic Acid‐Induced Experimental Colitis in …

F Sirinyıldız, S Unay, A Keskin - Journal of Biochemical and …, 2025 - Wiley Online Library
The aim of this study was to investigate the potential role of thymoquinone in the treatment of
inflammatory bowel disease (IBD) by examining the effects of various doses of …

[HTML][HTML] High-frequency ultrasound-assisted drug delivery of chia, cress, and flax conjugated hematite iron oxide nanoparticle for sono-photodynamic lung cancer …

A El-Kaream, S Ali, DFM Zedan… - Cancer …, 2024 - cancer-nano.biomedcentral.com
Sono-photodynamic therapy (SPDT), which combines photodynamic (PDT) and
sonodynamic (SDT) therapies with sensitizers, offers new avenues for cancer treatment …

[PDF][PDF] Combination therapy of metformin and atorvastatin against benzopyrene-induced lung cancer via inflammatory signaling pathway.

X Ning, S Zhang, Z Gao, A Li - General Physiology & Biophysics, 2024 - gpb.sav.sk
The most prevalent cause of lung cancer is smoking tobacco, but exposure to second hand
smoke, air pollution, and certain chemicals and substances at work can also raise the risk of …

Synthesis and Characterization of Thymoquinone‐Oxime (TQ‐Ox) from Thymoquinone and Evaluation of its Cytotoxic, Genotoxic, and Apoptotic Potential in Lung …

H Beyaztas, B Babaoglu, B Demirkol… - …, 2024 - Wiley Online Library
Abstract Intro: Thymoquinone (TQ), a compound derived from Nigella sativa, has been found
to impede cancer progression, including proliferation, migration, and invasion. Previous …

Nigella (Black Cumin, Black Seed)

PN Ravindran - Handbook of Spices in India: 75 Years of Research …, 2023 - Springer
Black cumin or black seed as Nigella sativa is more often called and is an important spice
and medicinal plant that probably originated in the Mediterranean and adjoining regions …