Quantum dots: bright and versatile in vitro and in vivo fluorescence imaging biosensors

KD Wegner, N Hildebrandt - Chemical Society Reviews, 2015 - pubs.rsc.org
Semiconductor quantum dots (QDs) have become important fluorescent probes for in vitro
and in vivo bioimaging research. Their nanoparticle surfaces for versatile bioconjugation …

Strategies for the intracellular delivery of nanoparticles

LYT Chou, K Ming, WCW Chan - Chemical society reviews, 2011 - pubs.rsc.org
The ability to target contrast agents and therapeutics inside cells is becoming important as
we strive to decipher the complex network of events that occur within living cells and design …

Designing multifunctional quantum dots for bioimaging, detection, and drug delivery

P Zrazhevskiy, M Sena, X Gao - Chemical Society Reviews, 2010 - pubs.rsc.org
The emerging field of bionanotechnology aims at revolutionizing biomedical research and
clinical practice via introduction of nanoparticle-based tools, expanding capabilities of …

Quantum dots as a platform for nanoparticle drug delivery vehicle design

CE Probst, P Zrazhevskiy, V Bagalkot, X Gao - Advanced drug delivery …, 2013 - Elsevier
Nanoparticle-based drug delivery (NDD) has emerged as a promising approach to
improving upon the efficacy of existing drugs and enabling the development of new …

Beyond labels: a review of the application of quantum dots as integrated components of assays, bioprobes, and biosensors utilizing optical transduction

WR Algar, AJ Tavares, UJ Krull - Analytica chimica acta, 2010 - Elsevier
A comprehensive review of the development of assays, bioprobes, and biosensors using
quantum dots (QDs) as integrated components is presented. In contrast to a QD that is …

Surface engineering of inorganic nanoparticles for imaging and therapy

J Nam, N Won, J Bang, H Jin, J Park, S Jung… - Advanced drug delivery …, 2013 - Elsevier
Many kinds of inorganic nanoparticles (NPs) including semiconductor, metal, metal oxide,
and lanthanide-doped NPs have been developed for imaging and therapy applications …

Delivering quantum dots to cells: bioconjugated quantum dots for targeted and nonspecific extracellular and intracellular imaging

V Biju, T Itoh, M Ishikawa - Chemical Society Reviews, 2010 - pubs.rsc.org
Bioconjugated nanomaterials offer endless opportunities to advance both
nanobiotechnology and biomedical technology. In this regard, semiconductor nanoparticles …

Quantum dot imaging platform for single-cell molecular profiling

P Zrazhevskiy, X Gao - Nature communications, 2013 - nature.com
Study of normal cell physiology and disease pathogenesis heavily relies on untangling the
complexity of intracellular molecular mechanisms and pathways. To achieve this goal …

Antibody vectors for imaging

T Olafsen, AM Wu - Seminars in nuclear medicine, 2010 - Elsevier
Noninvasive molecular imaging approaches include nuclear, optical, magnetic resonance
imaging, computed tomography, ultrasound, and photoacoustic imaging, which require …

Controlled antibody/(bio-) conjugation of inorganic nanoparticles for targeted delivery

JM Montenegro, V Grazu, A Sukhanova… - Advanced drug delivery …, 2013 - Elsevier
Arguably targeting is one of the biggest problems for controlled drug delivery. In the case
that drugs can be directed with high efficiency to the target tissue, side effects of medication …