Insecticide‐treated nets for preventing malaria

J Pryce, M Richardson… - Cochrane Database of …, 2018 - cochranelibrary.com
Background A previous version of this Cochrane Review identified that insecticide‐treated
nets (ITNs) are effective at reducing child mortality, parasite prevalence, and uncomplicated …

[HTML][HTML] Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria

J Achan, AO Talisuna, A Erhart, A Yeka… - Malaria journal, 2011 - Springer
Quinine remains an important anti-malarial drug almost 400 years after its effectiveness was
first documented. However, its continued use is challenged by its poor tolerability, poor …

[HTML][HTML] Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents

JE Kaplan, C Benson, KK Holmes, JT Brooks, A Pau… - MMWR Recomm …, 2009 - cdc.gov
This report updates and combines earlier versions of guidelines for the prevention and
treatment of opportunistic infections (OIs) in HIV-infected adults (ie, persons aged> 18 years) …

Common West African HLA antigens are associated with protection from severe malaria

AVS Hill, CEM Allsopp, D Kwiatkowski, NM Anstey… - Nature, 1991 - nature.com
A large case-control study of malaria in West African children shows that a human leucocyte
class I antigen (HLA-Bw53) and an HLA class II haplotype (DRB1* 1302–DQB1* 0501) …

[HTML][HTML] Indicators of life-threatening malaria in African children

K Marsh, D Forster, C Waruiru, I Mwangi… - New England journal …, 1995 - Mass Medical Soc
Background About 90 percent of the deaths from malaria are in African children, but criteria
to guide the recognition and management of severe malaria have not been validated in …

Severe falciparum malaria

World Health Organization - Transactions of the Royal Society of Tropical …, 2000 - Elsevier
A further meeting, sponsored by WHO, was held on 4-8 December 1995 in Geneva. The
purpose was to review in great detail the latest scientific evidence for, and practical …

Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes

JD Smith, CE Chitnis, AG Craig, DJ Roberts… - Cell, 1995 - cell.com
Plasmodium falciparum expresses on the host erythrocyte surface clonally variant antigens
and ligands that mediate adherence to endothelial receptors. Both are central to …

Thrombomodulin and its role in inflammation

EM Conway - Seminars in immunopathology, 2012 - Springer
The goal is to provide an extensive review of the physiologic role of thrombomodulin (TM) in
maintaining vascular homeostasis, with a focus on its anti-inflammatory properties. Data …

Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa

RW Snow, JA Omumbo, B Lowe, CS Molyneux… - The lancet, 1997 - thelancet.com
Background Malaria remains a major cause of mortality and morbidity in Africa. Many
approaches to malaria control involve reducing the chances of infection but little is known of …

Malaria pathogenesis

LH Miller, MF Good, G Milon - Science, 1994 - science.org
Malaria is a disease caused by repeated cycles of growth of the parasite Plasmodium in the
erythrocyte. Various cellular and molecular strategies allow the parasite to evade the human …