Traumatic brain injury: classification, models, and markers

D Najem, K Rennie… - … and cell biology, 2018 - cdnsciencepub.com
Traumatic brain injury (TBI) is a leading cause of morbidity and mortality worldwide. Due to
its high incidence rate and often long-term sequelae, TBI contributes significantly to …

Paroxysmal sympathetic hyperactivity during traumatic brain injury

AA Jafari, M Shah, S Mirmoeeni, MS Hassani… - Clinical neurology and …, 2022 - Elsevier
Traumatic brain injury (TBI) is one of the leading causes of disability, morbidity, and mortality
worldwide. Some of the more common etiologies of TBI include closed head injury …

[HTML][HTML] Increased intracranial pressure

VL Pinto, P Tadi, A Adeyinka - 2018 - europepmc.org
Objectives: Describe the causes of increased intracranial pressure. Review the clinical
presentation of a patient with increased intracranial pressure. Summarize the treatment of …

Vasopressors in trauma: a never event?

JE Richards, T Harris, MW Dünser… - Anesthesia & …, 2021 - journals.lww.com
Vasopressor use in severely injured trauma patients is discouraged due to concerns that
vasoconstriction will worsen organ perfusion and result in increased mortality and organ …

Long non-coding RNA HOTAIR in central nervous system disorders: new insights in pathogenesis, diagnosis, and therapeutic potential

J Wang, J Zhao, P Hu, L Gao, S Tian… - Frontiers in Molecular …, 2022 - frontiersin.org
Central nervous system (CNS) disorders, such as ischemic stroke, neurodegenerative
diseases, multiple sclerosis, traumatic brain injury, and corresponding neuropathological …

[HTML][HTML] Challenges of delirium management in patients with traumatic brain injury: from pathophysiology to clinical practice

SW Roberson, MB Patel, W Dabrowski… - Current …, 2021 - ncbi.nlm.nih.gov
Traumatic brain injury (TBI) can initiate a very complex disease of the central nervous
system (CNS), starting with the primary pathology of the inciting trauma and subsequent …

Versatile strategies for adult neurogenesis: avenues to repair the injured brain

J Zhao, S Liu, X Xiang, X Zhu - Neural Regeneration Research, 2024 - journals.lww.com
Brain injuries due to trauma or stroke are major causes of adult death and disability.
Unfortunately, few interventions are effective for post-injury repair of brain tissue. After a long …

Leveraging continuous vital sign measurements for real-time assessment of autonomic nervous system dysfunction after brain injury: a narrative review of current and …

J Podell, M Pergakis, S Yang, R Felix, G Parikh… - Neurocritical Care, 2022 - Springer
Subtle and profound changes in autonomic nervous system (ANS) function affecting
sympathetic and parasympathetic homeostasis occur as a result of critical illness. Changes …

Brain herniation and intracranial hypertension

A Tadevosyan, J Kornbluth - Neurologic clinics, 2021 - neurologic.theclinics.com
Intracranial pressure (ICP) is defined as the pressure measured within the intracranial vault.
This is a dynamic pressure consisting of a systolic, diastolic, and derived mean pressure and …

HMG-CoA reductase inhibitors for traumatic brain injury

K Katlowitz, S Gopinath, JC Navarro, C Robertson - Neurotherapeutics, 2023 - Elsevier
Traumatic brain injuries (TBIs) are associated with high morbidity and mortality due to both
the original insult as well as the destructive biological response that follows. Medical …