Strategies for identifying patients for deprescribing of blood pressure medications in routine practice: an evidence review

JP Sheppard, A Benetos, J Bogaerts, D Gnjidic… - Current Hypertension …, 2024 - Springer
Abstract Purpose of Review To summarise the evidence regarding which patients might
benefit from deprescribing antihypertensive medications. Recent Findings Older patients …

The association between antihypertensive treatment and serious adverse events by age and frailty: a cohort study

JP Sheppard, C Koshiaris, R Stevens… - PLoS …, 2023 - journals.plos.org
Background Antihypertensives are effective at reducing the risk of cardiovascular disease,
but limited data exist quantifying their association with serious adverse events, particularly in …

Risk of falls and fractures in individuals with cataract, age-related macular degeneration, or glaucoma

JY Tsang, A Wright, MJ Carr, C Dickinson… - JAMA …, 2024 - jamanetwork.com
Importance Three leading disease causes of age-related visual loss are cataract, age-
related macular degeneration (AMD), and glaucoma. Although all 3 eye diseases have been …

[HTML][HTML] Systematic review of multivariable prognostic models for outcomes at least 30 days after hip fracture finds 18 mortality models but no nonmortality models …

ME Walsh, PK Kristensen, TJ Hjelholt, C Hurson… - Journal of Clinical …, 2024 - Elsevier
Objectives Prognostic models have the potential to aid clinical decision-making after hip
fracture. This systematic review aimed to identify, critically appraise, and summarize …

Predicting the risk of acute kidney injury in primary care: derivation and validation of STRATIFY-AKI

C Koshiaris, L Archer, S Lay-Flurrie, KIE Snell… - British Journal of …, 2023 - bjgp.org
Background Antihypertensives reduce the risk of cardiovascular disease but are also
associated with harms including acute kidney injury (AKI). Few data exist to guide clinical …

Development and external validation of the eFalls tool: a multivariable prediction model for the risk of ED attendance or hospitalisation with a fall or fracture in older …

L Archer, SD Relton, A Akbari, K Best… - Age and …, 2024 - academic.oup.com
Background Falls are common in older adults and can devastate personal independence
through injury such as fracture and fear of future falls. Methods to identify people for falls …

Pharmacologic Treatment of Hypertension in Older Adults

OM Todd, M Knight, JA Jacobs… - Clinics in Geriatric …, 2024 - geriatric.theclinics.com
In the United States, 3 out of 4 people will develop hypertension during their lifetime. 1
Hypertension is the leading modifiable risk factor for cardiovascular disease which a …

Preventable deaths involving falls in England and Wales, 2013–22: a systematic case series of coroners' reports

K Song, C Portwood, J Jindal, D Launer… - Age and …, 2023 - academic.oup.com
Background Falls in older people are common, leading to significant harm including death.
Coroners have a duty to report cases where action should be taken to prevent future deaths …

Predicting 1 year readmission for heart failure: A comparative study of machine learning and the LACE index

X Song, Y Tong, F Xian, Y Luo, R Tong - ESC Heart Failure, 2024 - Wiley Online Library
Aims There is a lack of tools for accurately identifying the risk of readmission for heart failure
in elderly patients with arrhythmia. The aim of this study was to establish and compare the …

External Validation and Update of the Risk Prediction Model for Denosumab-Induced Hypocalcemia Developed From a Hospital-Based Administrative Database

K Ikegami, S Imai, O Yasumuro, M Tsuchiya… - JCO clinical cancer …, 2024 - ascopubs.org
PURPOSE Denosumab is used to treat patients with bone metastasis from solid tumors, but
sometimes causes severe hypocalcemia, so careful clinical management is important. This …