Dissecting cancer through mathematics: from the cell to the animal model

HM Byrne - Nature Reviews Cancer, 2010 - nature.com
This Timeline article charts progress in mathematical modelling of cancer over the past 50
years, highlighting the different theoretical approaches that have been used to dissect the …

Mathematical modeling of tumor-induced angiogenesis

NV Mantzaris, S Webb, HG Othmer - Journal of mathematical biology, 2004 - Springer
Cancer is a collection of diseases with the common feature of uncontrolled cellular growth.
Most tissues in the body can give rise to cancer, some even yield several types, and each …

Continuous and discrete mathematical models of tumor-induced angiogenesis

ARA Anderson, MAJ Chaplain - Bulletin of mathematical biology, 1998 - Elsevier
Angiogenesis, the formation of blood vessels from a pre-existing vasculature, is a process
whereby capillary sprouts are formed in response to externally supplied chemical stimuli …

Nonlinear modelling of cancer: bridging the gap between cells and tumours

JS Lowengrub, HB Frieboes, F Jin, YL Chuang, X Li… - …, 2009 - iopscience.iop.org
Despite major scientific, medical and technological advances over the last few decades, a
cure for cancer remains elusive. The disease initiation is complex, and including initiation …

[PDF][PDF] Volume-filling and quorum-sensing in models for chemosensitive movement

KJ Painter, T Hillen - Can. Appl. Math. Quart, 2002 - math.ualberta.ca
Chemotaxis is one of many mechanisms used by cells and organisms to navigate through
the environment, and has been found on scales varying from the microscopic to the …

Modelling and mathematical problems related to tumor evolution and its interaction with the immune system

N Bellomo, L Preziosi - Mathematical and Computer Modelling, 2000 - Elsevier
This paper provides a survey of mathematical models and methods dealing with the analysis
and simulation of tumor dynamics in competition with the immune system. The characteristic …

Mathematical modeling of tumor-induced angiogenesis

MAJ Chaplain, SR McDougall… - Annu. Rev. Biomed …, 2006 - annualreviews.org
Angiogenesis, the growth of a network of blood vessels, is a crucial component of solid
tumor growth, linking the relatively harmless avascular and the potentially fatal vascular …

Modelling aspects of cancer dynamics: a review

HM Byrne, T Alarcon, MR Owen… - … Transactions of the …, 2006 - royalsocietypublishing.org
Cancer is a complex disease in which a variety of factors interact over a wide range of
spatial and temporal scales with huge datasets relating to the different scales available …

A review of mathematical models for the formation of vascular networks

M Scianna, CG Bell, L Preziosi - Journal of theoretical biology, 2013 - Elsevier
Two major mechanisms are involved in the formation of blood vasculature: vasculogenesis
and angiogenesis. The former term describes the formation of a capillary-like network from …

[HTML][HTML] Cancer modeling: From mechanistic to data-driven approaches, and from fundamental insights to clinical applications

S Bekisz, L Geris - Journal of Computational Science, 2020 - Elsevier
Cancer is still one of the major causes of death worldwide. Even if its comprehension is
improving continuously, the complexity and heterogeneity of this group of diseases …