Biomaterials for drug delivery patches

LF Santos, IJ Correia, AS Silva, JF Mano - European Journal of …, 2018 - Elsevier
The limited efficiency of conventional drugs has been instigated the development of new
and more effective drug delivery systems (DDS). Transdermal DDS, are associated with …

Porous silicon for drug delivery applications and theranostics: recent advances, critical review and perspectives

T Kumeria, SJP McInnes, S Maher… - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: Porous silicon (pSi) engineered by electrochemical etching has been used as a
drug delivery vehicle to address the intrinsic limitations of traditional therapeutics …

Nanostructured porous silicon–polymer-based hybrids: from biosensing to drug delivery

LM Bonanno, E Segal - Nanomedicine, 2011 - Taylor & Francis
Organic–inorganic hybrids with controlled morphology at the nanometer scale represent an
exciting class of materials that can display unique properties that are culminated by the …

Silicon–polymer hybrid materials for drug delivery

SJP McInnes, NH Voelcker - Future medicinal chemistry, 2009 - Taylor & Francis
Silicon and its oxides are widely used in biomaterials research, tissue engineering and drug
delivery. These materials are highly biocompatible, easily surface functionalized, degrade …

Combination of iCVD and porous silicon for the development of a controlled drug delivery system

SJP McInnes, EJ Szili, SA Al-Bataineh… - … applied materials & …, 2012 - ACS Publications
We describe a pH responsive drug delivery system which was fabricated using a novel
approach to functionalize biodegradeable porous silicon (pSi) by initiated chemical vapor …

Material and structural behaviour of PMMA from low temperatures to over the glass transition: Quasi-static and dynamic loading

D Garcia-Gonzalez, A Rusinek, A Bendarma, R Bernier… - Polymer Testing, 2020 - Elsevier
This work aims at characterizing the mechanical behaviour of polymethyl-methacrylate
(PMMA) under high velocity impact conditions over a wide range of testing temperatures. To …

Luminescent Silicon Diatom Replicas: Self‐Reporting and Degradable Drug Carriers with Biologically Derived Shape for Sustained Delivery of Therapeutics

S Maher, M Alsawat, T Kumeria… - Advanced Functional …, 2015 - Wiley Online Library
Current development of drug microcarriers is mainly based on spherical shapes, which are
not biologically favorable geometries for complex interactions with biological systems …

Oriented nanofibrous polymer scaffolds containing protein‐loaded porous silicon generated by spray nebulization

JM Zuidema, T Kumeria, D Kim, J Kang… - Advanced …, 2018 - Wiley Online Library
Oriented composite nanofibers consisting of porous silicon nanoparticles (pSiNPs)
embedded in a polycaprolactone or poly (lactide‐co‐glycolide) matrix are prepared by spray …

From the mine to cancer therapy: natural and biodegradable theranostic silicon nanocarriers from diatoms for sustained delivery of chemotherapeutics

S Maher, T Kumeria, Y Wang, G Kaur… - Advanced …, 2016 - Wiley Online Library
Drug delivery using synthetic nanoparticles including porous silicon has been extensively
used to overcome the limitations of chemotherapy. However, their synthesis has many …

Controlled drug delivery from composites of nanostructured porous silicon and poly(L-lactide)

SJP McInnes, Y Irani, KA Williams, NH Voelcker - Nanomedicine, 2012 - Taylor & Francis
Aims: Porous silicon (pSi) and poly (l-lactide)(PLLA) both display good biocompatibility and
tunable degradation behavior, suggesting that composites of both materials are suitable …