Curcumin is the primary polyphenol in turmeric's curcuminoid class. It has a wide range of
therapeutic applications, such as anti-inflammatory, antioxidant, antidiabetic …

Abstract Thiamine (thiamin, B1) is a vitamin necessary for proper cell function. It exists in a
free form as a thiamine, or as a mono-, di-or triphosphate. Thiamine plays a special role in …

Diabetes is a risk factor for Alzheimer's disease (AD), which is also called type 3 diabetes
with insulin reduction and insulin resistance in AD patient brains. However, the molecular …

Thiamine (vitamin B1) is essential for the brain. This is attributed to the coenzyme role of
thiamine diphosphate (ThDP) in glucose and energy metabolism. The synthetic thiamine …

The need to protect neural tissue from toxins or other substances is as old as neural tissue
itself. Early recognition of this need has led to more than a century of investigation of the …

Thiamine, also known as vitamin B1, is an essential nutrient that plays a crucial role in
energy metabolism and overall health. It is a water-soluble vitamin that plays an important …

Depression is a mental disorder characterized by low mood, lack of motivation, negative
cognitive outlook, and sleep problems. Suicide may occur in severe cases, although suicidal …

Septic shock is associated with unacceptably high mortality rates, mainly in developing
countries. New adjunctive therapies have been explored to reduce global mortality related to …

This study investigated the effect of the bacterial endotoxin lipopolysaccharide (LPS) on
colonic uptake of thiamin pyrophosphate (TPP), the biologically active form of vitamin B1 that …

Mutations in the gene encoding the RNA/DNA-binding protein Fused in Sarcoma (FUS)
have been detected in familial amyotrophic lateral sclerosis (ALS) patients. FUS has been …