Micro total analysis systems for cell biology and biochemical assays

ML Kovarik, PC Gach, DM Ornoff, Y Wang… - Analytical …, 2012 - ACS Publications
Novel applications of micro total analysis systems (μTAS) are addressing fundamental
biological questions, creating new biomedical reagents, and developing innovative cell and …

Chemistry and the Worm: Caenorhabditis elegans as a Platform for Integrating Chemical and Biological Research

SE Hulme, GM Whitesides - Angewandte Chemie International …, 2011 - Wiley Online Library
This Review discusses the potential usefulness of the worm Caenorhabditis elegans as a
model organism for chemists interested in studying living systems. C. elegans, a 1 mm long …

Femtosecond laser nanoaxotomy lab-on-a-chip for in vivo nerve regeneration studies

SX Guo, F Bourgeois, T Chokshi, NJ Durr, MA Hilliard… - Nature …, 2008 - nature.com
A thorough understanding of nerve regeneration in Caenorhabditis elegans requires
performing femtosecond laser nanoaxotomy while minimally affecting the worm. We present …

Large-scale microfluidics providing high-resolution and high-throughput screening of Caenorhabditis elegans poly-glutamine aggregation model

S Mondal, E Hegarty, C Martin, SK Gökce… - Nature …, 2016 - nature.com
Next generation drug screening could benefit greatly from in vivo studies, using small animal
models such as Caenorhabditis elegans for hit identification and lead optimization. Current …

On the rheology of Pluronic F127 aqueous solutions

M Jalaal, G Cottrell, N Balmforth, B Stoeber - Journal of Rheology, 2017 - pubs.aip.org
The rheology of aqueous solutions of Pluronic F127 is studied as a function of concentration,
temperature, and shear rate. At sufficiently low temperatures, the solutions behave like …

[HTML][HTML] Microfluidics as a tool for C. elegans research

A San-Miguel, H Lu - WormBook: The Online Review of C. elegans …, 2018 - ncbi.nlm.nih.gov
Microfluidics has emerged as a set of powerful tools that have greatly advanced some areas
of biological research, including research using C. elegans. The use of microfluidics has …

Spatiotemporal Tracking of Near‐Infrared Fluorescent Single‐Walled Carbon Nanotubes in C. Elegans Nematodes Confined in a Microfluidics Platform

E Sharaga, A Hendler‐Neumark… - Advanced Materials …, 2024 - Wiley Online Library
Caenorhabditis elegans (C. elegans) nematodes are a powerful model organism for diverse
biological and biomedical studies, benefiting from their genetic similarities to humans, small …

Long-term high-resolution imaging of developing C. elegans larvae with microfluidics

W Keil, LM Kutscher, S Shaham, ED Siggia - Developmental cell, 2017 - cell.com
Long-term studies of Caenorhabditis elegans larval development traditionally require
tedious manual observations because larvae must move to develop, and existing …

[HTML][HTML] A portable low-cost long-term live-cell imaging platform for biomedical research and education

MP Walzik, V Vollmar, T Lachnit, H Dietz… - Biosensors and …, 2015 - Elsevier
Time-resolved visualization and analysis of slow dynamic processes in living cells has
revolutionized many aspects of in vitro cellular studies. However, existing technology …

Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans

BP Gupta, P Rezai - Micromachines, 2016 - mdpi.com
The nematode C. elegans (worm) is a small invertebrate animal widely used in studies
related to fundamental biological processes, disease modelling, and drug discovery. Due to …