The combination of radiation and immunotherapy is currently an exciting avenue of pre-
clinical and clinical investigation. The synergy between these two treatment modalities has …

Highlights•Tissue resident memory T cells (T RM) are the main surveyors of non-lymphoid
tissues.•T RM activate innate and adaptive immunity and establish an antiviral state within …

During unresolved infections, some viruses escape immunological control and establish a
persistant reservoir in certain cell types, such as human immunodeficiency virus (HIV), which …

The progressive loss of immunological memory during aging correlates with a reduced
proliferative capacity and shortened telomeres of T cells. Growing evidence suggests that …

Chronic viral infections are associated with hematopoietic suppression, bone marrow (BM)
failure, and hematopoietic stem cell (HSC) exhaustion. However, how persistent viral …

Lymphocytic choriomeningitis virus (LCMV) is a neglected rodent-borne zoonotic virus
distributed worldwide. Since serologic assays are limited to several laboratories, the disease …

Two of the most important contemporary emerging viruses that affect human health in Africa
are Ebola virus (EBOV) and Lassa virus (LASV). The 2013–2016 West African outbreak of …

Rodents (order Rodentia), followed by bats (order Chiroptera), comprise the largest
percentage of living mammals on earth. Thus, it is not surprising that these two orders …

Mouse models are important tools both for studying the pathogenesis of infectious diseases
and for the preclinical evaluation of vaccines and therapies against a wide variety of human …

Organ donors are sources of physiologically healthy organs and tissues for life-saving
transplantation, and have been recently used for human immunology studies which are …