It is now well known that non-coding RNAs (ncRNAs), rather than protein-coding transcripts,
are the preponderant RNA transcripts. NcRNAs, particularly microRNAs (miRNAs), long non …

Abstract MicroRNAs (miRNAs), small non-coding RNAs (ncRNAs) of about 22 nucleotides in
size, play important roles in gene regulation, and their dysregulation is implicated in human …

MicroRNAs (miRNA) are a group of small non-coding RNAs that regulate gene expression
at the RNA level. MicroRNAs have positive regulatory effects on protein translation …

Head and neck cancers (HNCs) are a group of heterogeneous tumors formed most
frequently from epithelial cells of the larynx, lips, oropharynx, nasopharynx, and mouth …

During malignant transformation, accumulated somatic mutations endow cancer cells with
increased invasiveness and immunogenicity. Under selective pressure, these highly …

Accumulating research suggests that the tumor immune microenvironment (TIME) plays an
essential role in regulation of tumor growth and metastasis. The cellular and molecular …

Background Triple negative breast cancer (TNBC) is known as hot immunogenic tumor. Yet,
it is one of the most aggressive BC subtypes. TNBC evolve several tactics to evade the …

Stimulating antitumor immunity is an attractive idea for suppressing tumors. CD4+ and CD8+
T cells as well as natural killer cells (NK) are the primary antitumor immune cells in the tumor …

In recent years, immunotherapy has been revolutionized by a new approach that works by
blocking receptors called immune checkpoints (IC). These molecules play a key role in …

Triple-negative breast cancer (TNBC) incidence rate has regularly risen over the last
decades and is expected to increase in the future. Finding novel treatment options with …