[HTML][HTML] Nanoemulsions for drug delivery

RJ Wilson, Y Li, G Yang, CX Zhao - Particuology, 2022 - Elsevier
Emulsions are liquid–liquid dispersions with one liquid phase dispersed in the other liquid
phase as small droplets. Nanoemulsions are nano-sized emulsions with sizes ranging from …

A critical review of synthesis procedures, applications and future potential of nanoemulsions

A Naseema, L Kovooru, AK Behera, KPP Kumar… - Advances in Colloid and …, 2021 - Elsevier
Applications of nanotechnology in various spheres have increased manifold as it offers
solution to unsolved problems with higher effectiveness. Nanoemulsions are one such …

[HTML][HTML] Multiple roles of chitosan in mucosal drug delivery: an updated review

P Mura, F Maestrelli, M Cirri, N Mennini - Marine Drugs, 2022 - mdpi.com
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after
cellulose, is the second biopolymer most abundant in nature, being the primary component …

[HTML][HTML] Nanoemulsions for “nose-to-brain” drug delivery

MC Bonferoni, S Rossi, G Sandri, F Ferrari, E Gavini… - Pharmaceutics, 2019 - mdpi.com
The blood–brain barrier (BBB) plays a fundamental role in protecting the brain from toxic
substances and therefore also controls and restricts the entry of therapeutic agents. The …

[HTML][HTML] Potential of chitosan and its derivatives for biomedical applications in the central nervous system

DD Ojeda-Hernández, AA Canales-Aguirre… - … in Bioengineering and …, 2020 - frontiersin.org
It is well known that the central nervous system (CNS) has a limited regenerative capacity
and that many therapeutic molecules cannot cross the blood brain barrier (BBB). The use of …

Targeted drug delivery to the brain via intranasal nanoemulsion: Available proof of concept and existing challenges

B Chatterjee, B Gorain, K Mohananaidu… - International journal of …, 2019 - Elsevier
Intranasal delivery has shown to circumvent blood-brain-barrier (BBB) and deliver the drugs
into the CNS at a higher rate and extent than other conventional routes. The mechanism of …

Recent expansions of novel strategies towards the drug targeting into the brain

A Alexander, M Agrawal, A Uddin… - International journal …, 2019 - Taylor & Francis
The treatment of central nervous system (CNS) disorders always remains a challenge for the
researchers. The presence of various physiological barriers, primarily the blood–brain …

[HTML][HTML] Intranasal nanoemulsions for direct nose-to-brain delivery of actives for CNS disorders

S Bahadur, DM Pardhi, J Rautio, JM Rosenholm… - Pharmaceutics, 2020 - mdpi.com
The treatment of various central nervous system (CNS) diseases has been challenging,
despite the rapid development of several novel treatment approaches. The blood–brain …

Nose-to-brain delivery

Z Wang, G Xiong, WC Tsang, AG Schätzlein… - … of Pharmacology and …, 2019 - ASPET
The global prevalence of neurologic disorders is rising, and yet we are still unable to deliver
most drug molecules, in therapeutic quantities, to the brain. The blood brain barrier consists …

[HTML][HTML] Intranasal delivery of nanoformulations: a potential way of treatment for neurological disorders

SU Islam, A Shehzad, MB Ahmed, YS Lee - Molecules, 2020 - mdpi.com
Although the global prevalence of neurological disorders such as Parkinson's disease,
Alzheimer's disease, glioblastoma, epilepsy, and multiple sclerosis is steadily increasing …