Pyrimidine nucleoside uridine plays a critical role in maintaining cellular function and energy
metabolism. In addition to its role in nucleoside synthesis, uridine and its derivatives …

Many countries in the world are stepping into the aging society with the challenge of the
increasing agin gpopulation. The physiological functions of the human body begins to …

Uridine metabolism is extensively reported to be involved in combating oxidative stress.
Redox-imbalance-mediated ferroptosis plays a pivotal role in sepsis-induced acute lung …

The effect of uridine on the myocardial ischemic and reperfusion injury was investigated. A
possible mechanism of its cardioprotective action was established. Two rat models were …

Background Metabolites secreted by the gut microbiota may play an essential role in
microbiota–gut–central nervous system crosstalk. In this study, we explored the changes …

Keratinocytes form the physical barrier of the skin and play an important role in the
inflammatory process. Amauroderma rugosum is an edible mushroom; however, its …

Aging is a major risk factor for neurodegenerative diseases, including amyotrophic lateral
sclerosis (ALS). As metabolic alterations are a hallmark of aging and have previously been …

BACKGROUND Nucleotides play an important role in the regulation of cellular energy and
protein homeostasis, which facilitate the repair, recovery and repletion of tissue function …

Pyrimidine nucleosides (PN) are abundant in mammalian milk and mainly involved in
glycogen deposition and lipid metabolism. To investigate the effects of maternal …

The effect of the activation of the mitochondrial ATP-dependent potassium channel
(mitoKATP) on the ultrastructure of rat lung in acute hypoxic hypoxia (7% of oxygen in …