[HTML][HTML] Nanoparticles for targeted brain drug delivery: what do we know?

RGR Pinheiro, AJ Coutinho, M Pinheiro… - International Journal of …, 2021 - mdpi.com
The blood–brain barrier (BBB) is a barrier that separates the blood from the brain tissue and
possesses unique characteristics that make the delivery of drugs to the brain a great …

Advances in the design of solid lipid nanoparticles and nanostructured lipid carriers for targeting brain diseases

C Tapeinos, M Battaglini, G Ciofani - Journal of Controlled Release, 2017 - Elsevier
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) comprise a
category of versatile drug delivery systems that have been used in the biomedical field for> …

[HTML][HTML] Nanotechnology-based drug delivery for central nervous system disorders

TT Nguyen, TTD Nguyen, TK Vo, MK Nguyen… - Biomedicine & …, 2021 - Elsevier
Drug delivery to central nervous system (CNS) diseases is very challenging since the
presence of the innate blood–brain barrier (BBB) and the blood-cerebrospinal fluid barrier …

Recent advancements in liposomes targeting strategies to cross blood-brain barrier (BBB) for the treatment of Alzheimer's disease

M Agrawal, DK Tripathi, S Saraf, S Saraf… - Journal of controlled …, 2017 - Elsevier
In this modern era, with the help of various advanced technologies, medical science has
overcome most of the health-related issues successfully. Though, some diseases still remain …

[HTML][HTML] Advances in developing therapeutic strategies for Alzheimer's disease

TT Nguyen, TTD Nguyen, TKO Nguyen, TK Vo - Biomedicine & …, 2021 - Elsevier
Alzheimer's disease (AD) is a progressive deterioration of brain function, initially
characterized by cognitive deficits, with loss of recent memory and language ability …

Factors controlling nanoparticle pharmacokinetics: an integrated analysis and perspective

SM Moghimi, AC Hunter… - Annual review of …, 2012 - annualreviews.org
Intravenously injected nanoparticulate drug carriers provide a wide range of unique
opportunities for site-specific targeting of therapeutic agents to many areas within the …

Liposome delivery systems for the treatment of Alzheimer's disease

C Ross, M Taylor, N Fullwood… - International journal of …, 2018 - Taylor & Francis
Alzheimer's disease (AD) will affect around 115 million people worldwide by the year 2050.
It is associated with the accumulation of misfolded and aggregated proteins (β-amyloid and …

The effect of nanoparticle uptake on cellular behavior: disrupting or enabling functions?

A Panariti, G Miserocchi, I Rivolta - Nanotechnology, science and …, 2012 - Taylor & Francis
Nanoparticles (NPs) are materials with overall dimensions in the nanoscale range. They
have unique physicochemical properties, and have emerged as important players in current …

[HTML][HTML] Surface-modified lipid nanocarriers for crossing the blood-brain barrier (BBB): A current overview of active targeting in brain diseases

MI Teixeira, CM Lopes, MH Amaral, PC Costa - Colloids and Surfaces B …, 2023 - Elsevier
The blood-brain barrier (BBB) restricts the access of therapeutic agents to the brain,
complicating the treatment of neurological diseases, such as Alzheimer's disease (AD) …

Treatment of neurodegenerative disorders through the blood–brain barrier using nanocarriers

N Poovaiah, Z Davoudi, H Peng, B Schlichtmann… - Nanoscale, 2018 - pubs.rsc.org
Neurodegenerative diseases refer to disorders of the central nervous system (CNS) that are
caused by neuronal degradations, dysfunctions, or death. Alzheimer's disease, Parkinson's …