The identification of molecular agents inhibiting specific functions in cancer cells
progression is considered as one of the most successful plans in cancer treatment. The …

α, β-Unsaturated chalcone moieties and quinoline scaffolds play an important role in
medicinal chemistry, especially in the identification and development of potential anticancer …

Quinoline is an efficient scaffold for anticancer drug development as its derivatives have
shown potent results through several mechanisms like growth regulators through “apoptosis …

Lung cancer is the second most common cause of morbidity and mortality among cancer
types worldwide, with non-small cell lung cancer (NSCLC) representing the majority of most …

Herein, we synthesized some new fused [1, 2, 3] triazolo-pyrrolo [1, 2-a] pyrido [4, 3-d]
pyrimidines via click chemistry followed by carbon-carbon bond coupling as key approach …

The quinoline ring system has long been known as a versatile nucleus in the design and
synthesis of biologically active compounds. Currently, more than one hundred quinoline …

A new series of benzo-and tetrahydro benzo-[h] quinoline bearing a flexible (dimethylamino)
ethylcarboxamide side chain was designed and synthesized as DNA-intercalating antitumor …

Hexahydroquinoline (HHQ) scaffold was constructed and recruited for development of new
series of anticancer agents. Thirty-two new compounds were synthesised where x-ray …

Quinoline and its derivatives comprise an important group of heterocyclic compounds that
exhibits a wide range of pharmacological properties such as antibacterial, antiviral …

Novel thienoquinoline carboxamide-chalcone derivatives were prepared via the cyclization
of acylated chalcones and 2-mercaptoquinoline-3-carbaldehyde in DMF with K 2 CO 3 …