Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities
E Lubos, J Loscalzo, DE Handy - 2011 - liebertpub.com
Reactive oxygen species, such as superoxide and hydrogen peroxide, are generated in all
cells by mitochondrial and enzymatic sources. Left unchecked, these reactive species can …
cells by mitochondrial and enzymatic sources. Left unchecked, these reactive species can …
Cell-based assays: fuelling drug discovery
E Michelini, L Cevenini, L Mezzanotte, A Coppa… - Analytical and …, 2010 - Springer
It has been estimated that over a billion dollars in resources can be consumed to obtain
clinical approval, and only a few new chemical entities are approved by the US Food and …
clinical approval, and only a few new chemical entities are approved by the US Food and …
Current standing and future prospects for the technologies proposed to transform toxicity testing in the 21st century
E van Vliet - ALTEX-Alternatives to animal experimentation, 2011 - altex.org
Abstract The National Academy of Sciences publication, Toxicity Testing in the 21st Century:
A Vision and a Strategy, proposes a paradigm shift in toxicology from current animal-based …
A Vision and a Strategy, proposes a paradigm shift in toxicology from current animal-based …
Effects of catechin and epicatechin on superoxide dismutase and glutathione peroxidase activity, in vivo
YV Simos, II Verginadis, IK Toliopoulos… - Redox …, 2012 - Taylor & Francis
Objectives The objective of this study was to investigate the effects of catechin and
epicatechin on the activity of the endogenous antioxidant enzymes superoxide dismutase …
epicatechin on the activity of the endogenous antioxidant enzymes superoxide dismutase …
The protective effect of daidzein on high glucose-induced oxidative stress in human umbilical vein endothelial cells
MH Park, JW Ju, M Kim, JS Han - Zeitschrift für Naturforschung C, 2016 - degruyter.com
Endothelial cell dysfunction is considered a major cause of vascular complications in
diabetes. In the present study, we investigated the protective effect of daidzein, a natural …
diabetes. In the present study, we investigated the protective effect of daidzein, a natural …
Comments on the mechanisms of action of radiation protective agents: basis components and their polyvalence
MV Vasin - SpringerPlus, 2014 - Springer
Purpose These comments suggest a division of radiation protective agents on the grounds
of their mechanism of action that increase the radio resistance of an organism. Conclusion …
of their mechanism of action that increase the radio resistance of an organism. Conclusion …
Potent antioxidative activity of Vineatrol® 30 grapevine-shoot extract
C Mueller, K Ullmann, A Wilkens… - Bioscience …, 2009 - jstage.jst.go.jp
The health promoting effects of a grapevine-shoot extract named Vineatrol® 30, which
contains resveratrol (Resv) as well as considerable amounts of Resv oligomers, have …
contains resveratrol (Resv) as well as considerable amounts of Resv oligomers, have …
Genistein alleviates radiation-induced pneumonitis by depressing Ape1/Ref-1 expression to down-regulate inflammatory cytokines
GD Liu, L Xia, JW Zhu, S Ou, MX Li, Y He… - Cell biochemistry and …, 2014 - Springer
The aim of the study was to investigate the role of genistein in alleviating radiation-induced
pneumonitis (RIP) through down-regulating levels of the inflammatory cytokines by inhibiting …
pneumonitis (RIP) through down-regulating levels of the inflammatory cytokines by inhibiting …
Космос. Радиация. Человек (Радиационный барьер в межпланетных полетах)
ИБ Ушаков - 2021 - elibrary.ru
Главный барьер дальнейшего проникновения человека в космос-радиация различных
источников: галактические и солнечные космические лучи. Смоделировать всё на …
источников: галактические и солнечные космические лучи. Смоделировать всё на …
Thiopurines Induce Oxidative Stress in T‐Lymphocytes: A Proteomic Approach
M Misdaq, S Ziegler, N von Ahsen… - Mediators of …, 2015 - Wiley Online Library
Thiopurines are extensively used immunosuppressants for the treatment of inflammatory
bowel disease (IBD). The polymorphism of thiopurine S‐methyltransferase (TPMT) …
bowel disease (IBD). The polymorphism of thiopurine S‐methyltransferase (TPMT) …