Nanomaterials for in vivo imaging

BR Smith, SS Gambhir - Chemical reviews, 2017 - ACS Publications
In vivo imaging, which enables us to peer deeply within living subjects, is producing
tremendous opportunities both for clinical diagnostics and as a research tool. Contrast …

Toxicity of nanomaterials

S Sharifi, S Behzadi, S Laurent, ML Forrest… - Chemical Society …, 2012 - pubs.rsc.org
Nanoscience has matured significantly during the last decade as it has transitioned from
bench top science to applied technology. Presently, nanomaterials are used in a wide …

Delivering nanomedicine to solid tumors

RK Jain, T Stylianopoulos - Nature reviews Clinical oncology, 2010 - nature.com
Recent advances in nanotechnology have offered new hope for cancer detection,
prevention, and treatment. While the enhanced permeability and retention effect has served …

An activatable polymeric reporter for near‐infrared fluorescent and photoacoustic imaging of invasive cancer

Q Li, S Li, S He, W Chen, P Cheng, Y Zhang… - Angewandte …, 2020 - Wiley Online Library
Discriminative detection of invasive and noninvasive breast cancers is crucial for their
effective treatment and prognosis. However, activatable probes able to do so in vivo are …

Peptide-functionalized gold nanoparticles: versatile biomaterials for diagnostic and therapeutic applications

J Zong, SL Cobb, NR Cameron - Biomaterials science, 2017 - pubs.rsc.org
Colloidal gold solutions have been used for centuries in a wide variety of applications
including staining glass and in the colouring of ceramics. More recently, gold nanoparticles …

Peptide-based nanoprobes for molecular imaging and disease diagnostics

P Zhang, Y Cui, CF Anderson, C Zhang, Y Li… - Chemical Society …, 2018 - pubs.rsc.org
Pathological changes in a diseased site are often accompanied by abnormal activities of
various biomolecules in and around the involved cells. Identifying the location and …

Trypsin detection strategies: a review

J Kaur, PK Singh - Critical Reviews in Analytical Chemistry, 2022 - Taylor & Francis
Trypsin, a pancreatic serine protease, due to its narrow specificity and selectivity, has been
tremendously used in food technology, proteome analysis, modulating soy protein …

A pH‐responsive carrier system that generates NO bubbles to trigger drug release and reverse P‐glycoprotein‐mediated multidrug resistance

MF Chung, HY Liu, KJ Lin, WT Chia… - Angewandte Chemie …, 2015 - Wiley Online Library
Multidrug resistance (MDR) resulting from the overexpression of drug transporters such as P‐
glycoprotein (Pgp) increases the efflux of drugs and thereby limits the effectiveness of …

Gold-nanoparticle-based biosensors for detection of enzyme activity

E Hutter, D Maysinger - Trends in pharmacological sciences, 2013 - cell.com
Optimal enzyme activity is essential for maintenance of physiological homeostasis. A variety
of both non-genetic and genetic disruptions can excessively activate or silence intrinsic …

Avoiding thiol compound interference: a nanoplatform based on high‐fidelity Au–Se bonds for biological applications

B Hu, F Kong, X Gao, L Jiang, X Li, W Gao… - Angewandte …, 2018 - Wiley Online Library
Abstract Gold nanoparticles (Au NPs) assembled through Au− S covalent bonds have been
widely used in biomolecule‐sensing technologies. However, during the process, detection …