Gadolinium-based contrast agent accumulation and toxicity: an update

J Ramalho, RC Semelka, M Ramalho… - American Journal …, 2016 - Am Soc Neuroradiology
In current practice, gadolinium-based contrast agents have been considered safe when
used at clinically recommended doses in patients without severe renal insufficiency. The …

25 years of contrast-enhanced MRI: developments, current challenges and future perspectives

J Lohrke, T Frenzel, J Endrikat, FC Alves, TM Grist… - Advances in …, 2016 - Springer
In 1988, the first contrast agent specifically designed for magnetic resonance imaging (MRI),
gadopentetate dimeglumine (Magnevist®), became available for clinical use. Since then, a …

Survey of deep learning in breast cancer image analysis

TG Debelee, F Schwenker, A Ibenthal, D Yohannes - Evolving Systems, 2020 - Springer
Computer-aided image analysis for better understanding of images has been time-honored
approaches in the medical computing field. In the conventional machine learning approach …

Applications and potential toxicity of magnetic iron oxide nanoparticles

G Liu, J Gao, H Ai, X Chen - Small, 2013 - Wiley Online Library
Owing to their unique physical and chemical properties, magnetic iron oxide nanoparticles
have become a powerful platform in many diverse aspects of biomedicine, including …

Sialic acid-engineered mesoporous polydopamine nanoparticles loaded with SPIO and Fe3+ as a novel theranostic agent for T1/T2 dual-mode MRI-guided combined …

G Shu, M Chen, J Song, X Xu, C Lu, Y Du, M Xu… - Bioactive materials, 2021 - Elsevier
Hepatic cancer is a serious disease with high morbidity and mortality. Theranostic agents
with effective diagnostic and therapeutic capability are highly needed for the treatment of …

Breast cancer detection using automated whole breast ultrasound and mammography in radiographically dense breasts

KM Kelly, J Dean, WS Comulada, SJ Lee - European radiology, 2010 - Springer
Purpose Mammography, the standard method of breast cancer screening, misses many
cancers, especially in dense-breasted women. We compared the performance and …

Gadolinium as a new emerging contaminant of aquatic environments

J Rogowska, E Olkowska, W Ratajczyk… - Environmental …, 2018 - Wiley Online Library
Since the 1980s, gadolinium (Gd)–based contrast agents (GBCAs) have been routinely
used in magnetic resonance imaging as stable chelates of the Gd3+ ion, without toxic …

MRI contrast agents: basic chemistry and safety

D Hao, T Ai, F Goerner, X Hu… - Journal of Magnetic …, 2012 - Wiley Online Library
Magnetic resonance imaging (MRI) contrast agents are pharmaceuticals used widely in MRI
examinations. Gadolinium‐based MRI contrast agents (GBCAs) are by far the most …

High signal intensity in globus pallidus and dentate nucleus on unenhanced T1-weighted MR images: evaluation of two linear gadolinium-based contrast agents

J Ramalho, M Castillo, M AlObaidy, RH Nunes… - Radiology, 2015 - pubs.rsna.org
Purpose To determine if a correlation exists between the number of previous enhanced
magnetic resonance (MR) imaging examinations and high signal intensity in the globus …

Gadolinium (III) complexes as MRI contrast agents: ligand design and properties of the complexes

P Hermann, J Kotek, V Kubíček, I Lukeš - Dalton Transactions, 2008 - pubs.rsc.org
Magnetic resonance imaging is a commonly used diagnostic method in medicinal practice
as well as in biological and preclinical research. Contrast agents (CAs), which are often …