Single-cell sequencing (SCS) is an emerging high-throughput technology that can be used
to study the genomics, transcriptomics, and epigenetics at a single cell level. SCS is widely …

Over the last decades, transcriptome profiling emerged as one of the most powerful
approaches in oncology, providing prognostic and predictive utility for cancer management …

Background The immature neonatal fecal microbiota substantially impacts the development
of gut health and greatly increases the risk of disease. Developing effective strategies to …

Gliomas are the most common and lethal primary malignant tumor of the brain. Routine
treatment including surgical resection, chemotherapy, and radiotherapy produced limited …

Existing therapeutic strategies for gliomas are restricted; hence, exploration for novel
diagnostic indicator and treatment is essential. Here, we performed bioinformatic analyses …

Background Cytotoxic T-lymphocyte associated protein 4 (CTLA4) inhibitors have been
shown to significantly prolong the overall survival (OS) in a wide range of cancers. However …

The new technology of single-cell RNA sequencing (scRNA-seq) can yield valuable insights
into gene expression and give critical information about the cellular compositions of complex …

Recent multi-omics studies, including proteomics, transcriptomics, genomics, and
metabolomics have revealed the critical role of post-translational modifications (PTMs) in the …

Aging has a significant role in the proliferation and development of cancers. This study
explored the expression profiles, prognostic value, and potential roles of aging-related …

Type B adverse drug reactions (ADRs) are iatrogenic immune-mediated syndromes with
mechanistic etiologies that remain incompletely understood. Some of the most severe ADRs …