It is well established that natural killer (NK) cells are involved in both innate and adaptive
immunity. Indeed, they can recognize molecules induced at the cell surface by stress signals …

Natural killer (NK) cells play a pivotal role in the immune system, especially in the
recognition and clearance of cancer cells and infected cells. Their effector function is …

BACKGROUND While the human fetal immune system defaults to a program of tolerance,
there is a concurrent need for protective immunity to meet the antigenic challenges …

Triple-negative breast cancer (TNBC) is the most invasive form of breast cancer due to an
absence of estrogen (ER), progesterone (PR), and human epidermal growth factor-2 (HER2) …

Autoimmune hepatitis (AIH) is an immune‐mediated liver disease currently treated by
immunosuppressive medications with significant side effects. Thus, novel mechanistic …

Human C‐type lectin‐like CD161 is a type‐II transmembrane protein expressed on the
surface of various lymphocytes across innate and adaptive immune systems. CD161+ T …

Diverse populations of natural killer (NK) cells have been identified in circulating peripheral
blood and a wide variety of different tissues and organs. These tissue-resident NK cell …

Lectin-like transcript 1 (LLT1) expression by tumor cells contributes to immune evasion,
thereby emerging as a natural killer (NK) cell-mediated immunotherapeutic target. This study …

Killer cell lectin-like receptors (KLRs) are C-type lectin-like glycoproteins encoded by genes
clustered in the natural killer gene complex (NKC) located on the short arm of human …

The interaction of lectin-like transcript 1 (LLT1) with CD161 inhibits Natural Killer cell
activation. Overexpression of LLT1 contributes to the immunosuppressive properties of …