Trisomic and monosomic (aneuploid) embryos account for at least 10% of human
pregnancies and, for women nearing the end of their reproductive lifespan, the incidence …

The field of single-cell genomics is advancing rapidly and is generating many new insights
into complex biological systems, ranging from the diversity of microbial ecosystems to the …

Objective To provide a detailed description of the current oocyte vitrification status as a
means of elective fertility preservation (EFP). Design Retrospective observational …

Objective To determine the clinical value of preimplantation genetic diagnosis for
aneuploidy screening (PGD-A) in women of advanced maternal age (AMA; between 38 and …

Eggs and sperm develop through a specialized cell division called meiosis. During meiosis,
the number of chromosomes is reduced by two sequential divisions in preparation for …

STUDY QUESTION Does preimplantation genetic testing for aneuploidy (PGT-A) by
comprehensive chromosome screening (CCS) of the first and second polar body to select …

BACKGROUND Advanced maternal age is associated with reduced fertility and adverse
pregnancy outcomes. This review details recent developments in our understanding of the …

OBJECTIVE: To evaluate the results of controlled ovarian hyperstimulation (COH) for oocyte
vitrification to preserve fertility for medical and nonmedical indications. DESIGN: A …

BACKGROUND Since it was established in 1997, the ESHRE PGD Consortium has been
collecting data from international preimplantation genetic diagnosis (PGD) centres. Ten …

STUDY QUESTION Is preimplantation genetic diagnosis for aneuploidy (PGD-A) with
analysis of all chromosomes during assisted reproductive technology (ART) clinically and …