Relation between characteristic temperature and elution temperature in temperature programmed gas chromatography-part I: Influence of initial temperature and …

T Brehmer, P Boeker, M Wüst, J Leppert - Journal of Chromatography A, 2023 - Elsevier
The development of new analytical methods can save resources, time and costs if there are
prediction tools like computer simulation which support the optimization process. In GC the …

Chromatographic parameters: Characteristic parameters of solute retention–an insightful description of column properties

LM Blumberg - Journal of Chromatography A, 2022 - Elsevier
Previously introduced characteristic parameters of solute retention–the solute characteristic
temperature (T char) and thermal constant (θ) in GC as well as the characteristic solvent …

Retention database for prediction, simulation, and optimization of GC separations

T Brehmer, B Duong, M Marquart, L Friedemann… - ACS …, 2023 - ACS Publications
This work presents an open source database with suitable retention parameters for
prediction and simulation of GC separations and gives a short introduction to three common …

Estimation of retention parameters from temperature programmed gas chromatography

J Leppert, T Brehmer, M Wüst, P Boeker - Journal of Chromatography A, 2023 - Elsevier
A fast and reliable method is presented to evaluate retention parameters of the distribution-
centric 3-parameter model from temperature programed gas chromatographic …

[HTML][HTML] Simulation of gas chromatographic separations and estimation of distribution-centric retention parameters using linear solvation energy relationships

T Brehmer, B Duong, P Boeker, M Wüst… - … of Chromatography A, 2024 - Elsevier
For method development in gas chromatography, suitable computer simulations can be very
helpful during the optimization process. For such computer simulations retention parameters …

[PDF][PDF] GasChromatographySimulator. jl

J Leppert - Journal of Open Source Software, 2022 - joss.theoj.org
Gas chromatography (GC) is a technique used in analytical chemistry to separate a mixture
of vaporizable substances by injecting the mixture into a gas stream (mobile phase), which …

Improvement of chiral separation efficiency through temperature control during one time high performance liquid chromatography analysis

DB Eun, YH Jeong, JJ Ryoo - Chirality, 2022 - Wiley Online Library
This study examined how manual temperature control affects the separation of two
enantiomers of five racemic mixtures using high‐performance liquid chromatography …

Simulation of the effects of negative thermal gradients on separation performance of gas chromatography

J Leppert, LM Blumberg, M Wüst, P Boeker - Journal of Chromatography A, 2021 - Elsevier
The effect of a gradient of solute velocity on the chromatographic separation of closely
spaced solutes is investigated by usage of a simulation. The concept of the ideal basic …

[HTML][HTML] A hyper-fast gas chromatograph coupled to an ion mobility spectrometer with high repetition rate and flow-optimized ion source to resolve the short …

A Nitschke, M Hitzemann, J Winkelholz, AT Kirk… - … of Chromatography A, 2024 - Elsevier
By combining the high selectivity of a gas chromatograph (GC) with the high sensitivity and
decent selectivity of an ion mobility spectrometer (IMS), GC-IMS have become increasingly …

Comparison of the dynamic thermal gradient to temperature-programmed conditions in gas chromatography using a stochastic transport model

S Avila, HD Tolley, BD Iverson, AR Hawkins… - Analytical …, 2021 - ACS Publications
This paper compares dynamic (ie, temporally changing) thermal gradient gas
chromatography (GC) to temperature-programmed GC using a previously published …