Responsible, practical genomic data sharing that accelerates research

JB Byrd, AC Greene, DV Prasad, X Jiang… - Nature Reviews …, 2020 - nature.com
Data sharing anchors reproducible science, but expectations and best practices are often
nebulous. Communities of funders, researchers and publishers continue to grapple with …

[HTML][HTML] Generative AI in medical practice: in-depth exploration of privacy and security challenges

Y Chen, P Esmaeilzadeh - Journal of Medical Internet Research, 2024 - jmir.org
As advances in artificial intelligence (AI) continue to transform and revolutionize the field of
medicine, understanding the potential uses of generative AI in health care becomes …

Blockchain for genomics: a systematic literature review

M Alghazwi, F Turkmen, J Van Der Velde… - … : Research and Practice, 2022 - dl.acm.org
Human genomic data carry unique information about an individual and offer unprecedented
opportunities for healthcare. The clinical interpretations derived from large genomic datasets …

[HTML][HTML] The children's brain tumor network (CBTN)-Accelerating research in pediatric central nervous system tumors through collaboration and open science

JV Lilly, JL Rokita, JL Mason, T Patton, S Stefankiewiz… - Neoplasia, 2023 - Elsevier
Pediatric brain tumors are the leading cause of cancer-related death in children in the
United States and contribute a disproportionate number of potential years of life lost …

Enhancing research through the use of the genotype-tissue expression (GTEx) database

AG Stanfill, X Cao - Biological research for nursing, 2021 - journals.sagepub.com
Despite a growing interest in multi-omic research, individual investigators may struggle to
collect large-scale omic data, particularly from human subjects. Publicly available datasets …

OSIRIS: a minimum data set for data sharing and interoperability in oncology

J Guerin, YH Laizet, V Le Texier, L Chanas… - JCO Clinical Cancer …, 2021 - ascopubs.org
PURPOSE Many institutions throughout the world have launched precision medicine
initiatives in oncology, and a large amount of clinical and genomic data is being produced …

Using big data in pediatric oncology: Current applications and future directions

A Major, SM Cox, SL Volchenboum - Seminars in Oncology, 2020 - Elsevier
Pediatric cancer is a rare disease with a low annual incidence, which presents a significant
challenge in being able to collect enough data to fuel clinical discoveries. Big data registry …

Orchestrating and sharing large multimodal data for transparent and reproducible research

A Mammoliti, P Smirnov, M Nakano, Z Safikhani… - Nature …, 2021 - nature.com
Reproducibility is essential to open science, as there is limited relevance for findings that
can not be reproduced by independent research groups, regardless of its validity. It is …

Prediction of cancer driver genes and mutations: the potential of integrative computational frameworks

M Nourbakhsh, K Degn, A Saksager… - Briefings in …, 2024 - academic.oup.com
The vast amount of available sequencing data allows the scientific community to explore
different genetic alterations that may drive cancer or favor cancer progression. Software …

A molecular map of lung neuroendocrine neoplasms

AAG Gabriel, E Mathian, L Mangiante, C Voegele… - …, 2020 - academic.oup.com
Abstract Background Lung neuroendocrine neoplasms (LNENs) are rare solid cancers, with
most genomic studies including a limited number of samples. Recently, generating the first …